MorphologyMorphology1026-35432949-2556Eco-Vector10181110.34922/AE.2020.158.4.007Research ArticleCHANGES IN THE MORPHOMETRIC PARAMETERS OF THE BASILAR ARTERY WALL WHEN ITS COURSE IS GEOMETRICALLY ABNORMAL (KINKING AND COILING OF THE BASILAR ARTERY)AlekseevaN. T.alexeevant@list.ruKlochkovaS. V.swetlana.chava@yandex.ruNikityukD. B.dimitrynik@mail.ruKarandeevaA. M.arina_karandeeva@mail.ruKvaratskheliyaA. G.anna_kvar_83@mail.ruN. N. Burdenko Voronezh State Medical UniversityI. M. Sechenov First Moscow State Medical University (Sechenov University)Federal Research Centre of Nutrition, Biotechnology and Food SafetyI. M. Sechenov First Moscow State Medical University (Sechenov University)151020201584-5485227022022Copyright © 2020, Alekseeva N.T., Klochkova S.V., Nikityuk D.B., Karandeeva A.M., Kvaratskheliya A.G.2020Objective - to reveal the pattern of changes in the morphometric parameters of the basilar artery when the geometric configuration of its course alters with the formation of an acute angle, spiral or loop. Material and methods. We studied 16 non-fixed human brain specimens. Anatomy of the basilar artery was studied by methods of macro- and micro-preparation, angiomorphometry was carried out with subsequent processing of the results of the study. Results. During angiomorphometry of 16 basilar arteries, normal straight course of the vessel was detected in 68,75 % of the cases. The value of the elastic properties index was 0,33±0,01. In 31,25 % of cases, a change in the geometric configuration of the course of the basilar artery was revealed. The basilar artery kinking was formed in 40 % and coiling - in 60 % of the total number of all cases with abnormal vessel course. The value of the elastic properties index was 0,34±0,01, which is not significantly different from the average values for muscle-type arteries. The study of the length, wall thickness, outer diameter and lumen diameter of the vessels showed a significant excess of these parameters in comparison with the vessels with normal linear course. Conclusions. The data obtained during the study indicate an increase in the outer diameter of the basilar artery, as well as an increase in the thickness of the vascular wall and the inner lumen in the case of kinking or coiling.basilar arterykinkingcoilingvariant anatomypathological arterial tortuosityбазилярная артериякинкингкойлингвариантная анатомияпатологическая извитость артерии[Железкова А. А., Скоробогатов Ю. Ю., Филатова О. В. Возрастные особенности линейной и объемной скорости кровотока во внутренних сонных артериях // Известия Алтайского государственного университета. 2010. № 3-2. С. 29-34.][Иванов Д. В., Фомкина О. А. Исследование механических свойств артерий Виллизиевого многоугольника // Российский журнал биомеханики. 2008. Т. 12, № 4. С. 75-83.][Пивченко П. Г., Трушель Н. А. Вариантная анатомия сосудов Виллизиева круга // Здравоохранение (Минск). 2010. № 5. С. 22-24.][Терегулов Ю. Э., Маянская С. Д., Терегулова Е. Т. Изменения эластических свойств артерий и гемодинамические процессы // Практическая медицина. 2017. № 2 (103). С. 14-20.][Трушель Н. А. Гемодинамические и морфологические предпосылки развития цереброваскулярной патологии // Журнал анатомии и гистопатологии. 2016. Т. 5, № 4. С. 69-73.][Шмырев В. И., Казанцева И. В. Влияние патологической извитости магистральных артерий головы на мозговой кровоток // Кремлевская медицина. Клинический вестник. 2008. № 2. С. 50-53.][Asmar R., Rudnichi A., Blacher I. et al. Pulse pressure and aortic pulse wave are markers of cardiovascular risk in hypertensive populations // Am. J. Hypertens. 2001. Vol. 14, № 2. Р. 91-97.][Beigelman R., Izaguirre A. M., Robles M., Grana D. R., Ambrosio G., Milei J. Are kinking and coiling of carotid artery congenital or acquired? / R. Beigelman, // Angiology. 2010. Vol. 61, № 1. P. 107-112.][Metz H., Murray-Leslie R. M., Bannister R. G., Bull J. W., Marshall J. Kinking of the ICA in relation o cerebro vascular disease // Lancet. 1961. Vol. 25. P. 424-426.][Posadzy-Malaczynska A., Kosch M., Hausberg M. et al. Arterial distensibility, intima media thickness and pulse wave velocity after renal transplantation and in dialysis normotensive patients // Int. Angiol. 2005. Vol. 2, № 1. Р. 89-94.][Togay-Işikay C., Kim J., Betterman K., Andrews C., Meads D., Tesh P., Tegeler C., Oztuna D. Carotid artery tortuosity, kinking, coiling: stroke risk factor, marker, or curiosity? // Acta Neurol. Belg. 2005. Vol. 105, № 2. P. 68-72.][Truelsen T., Begg S., Mathers C. The global burden of cerebrovascular disease / Glob. Burd. Dis. 2000. P. 1-67.]