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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Morphology</journal-id><journal-title-group><journal-title xml:lang="en">Morphology</journal-title><trans-title-group xml:lang="ru"><trans-title>Морфология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1026-3543</issn><issn publication-format="electronic">2949-2556</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">397671</article-id><article-id pub-id-type="doi">10.17816/morph.397671</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">SEXUAL DIMORPHISM OF MAJOR SALIVARY GLANDS IN RODENTS</article-title><trans-title-group xml:lang="ru"><trans-title>ПОЛОВОЙ ДИМОРФИЗМ БОЛЬШИХ СЛЮННЫХ ЖЕЛЕЗ У ГРЫЗУНОВ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ivanova</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Иванова</surname><given-names>Вера Владимировна</given-names></name></name-alternatives><bio xml:lang="en"><p>Department of Morphology and General Pathology</p></bio><bio xml:lang="ru"><p>кафедра морфологии и общей патологии</p></bio><email>ivvera92@rambler.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mil’to</surname><given-names>I. V.</given-names></name><name xml:lang="ru"><surname>Мильто</surname><given-names>Иван Васильевич</given-names></name></name-alternatives><bio xml:lang="en"><p>Department of Morphology and General Pathology; Department of Biotechnology and Organic Chemistry</p></bio><bio xml:lang="ru"><p>кафедра биотехнологии и органической химии; кафедра морфологии и общей патологии</p></bio><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sukhodolo</surname><given-names>I. V.</given-names></name><name xml:lang="ru"><surname>Суходоло</surname><given-names>Ирина Владимировна</given-names></name></name-alternatives><bio xml:lang="en"><p>Department of Morphology and General Pathology</p></bio><bio xml:lang="ru"><p>кафедра морфологии и общей патологии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Serebryakova</surname><given-names>O. N.</given-names></name><name xml:lang="ru"><surname>Серебрякова</surname><given-names>Ольга Николаевна</given-names></name></name-alternatives><bio xml:lang="en"><p>Department of Morphology and General Pathology</p></bio><bio xml:lang="ru"><p>кафедра морфологии и общей патологии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Buzenkova</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Бузенкова</surname><given-names>Ангелина Владиславовна</given-names></name></name-alternatives><bio xml:lang="en"><p>Department of Morphology and General Pathology</p></bio><bio xml:lang="ru"><p>кафедра морфологии и общей патологии</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Siberian State Medical University</institution></aff><aff><institution xml:lang="ru">Сибирский государственный медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Siberian State Medical University</institution></aff><aff><institution xml:lang="ru">Национальный исследовательский Томский политехнический университет</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">National Research Tomsk Polytechnic University</institution></aff><aff><institution xml:lang="ru">Сибирский государственный медицинский университет</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2016</year></pub-date><volume>149</volume><issue>2</issue><issue-title xml:lang="en">VOL 149, NO2 (2016)</issue-title><issue-title xml:lang="ru">ТОМ 149, №2 (2016)</issue-title><fpage>89</fpage><lpage>95</lpage><history><date date-type="received" iso-8601-date="2023-05-09"><day>09</day><month>05</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, Эко-Вектор</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://j-morphology.com/1026-3543/article/view/397671">https://j-morphology.com/1026-3543/article/view/397671</self-uri><abstract xml:lang="en"><p>The review analyses the data on the structure of submandibular (SMG), parotid and sublingual salivary glands in rodents and on biologically active substances produced by them. The evidence is presented on the mutual influence of rodent major salivary glands (MSG) and the testes. Special attention is paid to gender differences of MSG in rodents, which are more fully apparent in mature individuals and are most pronounced in SMG. Sexual dimorphism is morphologically manifested in a larger size of secretory portions, the relative areas of granular and interlobular excretory ducts of SMG and greater number of granular cells of striated ducts of the sublingual glands in males. Biochemically sexual dimorphism is characterized by different amounts of biologically active substances secreted by the epithelial cells of secretory portions and granular cells of the ducts. Epidermal growth factor, nerve growth factor, kallikrein and other substances are synthesized in granular cells of the excretory ducts of all MSG in rodents, however, to the greatest extent - by SMG. The higher content of physiologically active substances in MSG saliva in males plays an important biological role.</p></abstract><trans-abstract xml:lang="ru"><p>В обзоре проанализированы сведения о строении поднижнечелюстных (ПНЧЖ), околоушных и подъязычных слюнных желез у грызунов и о вырабатываемых ими биологически активных веществах. Приведены данные о взаимном влиянии больших слюнных желез (БСЖ) и семенников у грызунов. Особое внимание уделено гендерным различиям БСЖ у грызунов, которые наиболее полно проявляются у половозрелых особей и максимально выражены в ПНЧЖ. Морфологические проявления полового диморфизма заключаются в большем размере концевых отделов, относительной площади междольковых и гранулярных выводных протоков ПНЧЖ, а также в большем количестве гранулярных клеток исчерченных протоков подъязычных желез у самцов. Биохимически половой диморфизм характеризуется различным уровнем секреции эпителиоцитами концевых отделов и гранулярными клетками протоков биологически активных веществ. Эпидермальный фактор роста, фактор роста нервов, калликреин и другие вещества синтезируются гранулярными клетками выводных протоков всех БСЖ у грызунов, однако, в наибольшей степени - ПНЧЖ. Более высокое содержание физиологически активных веществ в БСЖ и слюне у самцов имеет важное биологическое значение.</p></trans-abstract><kwd-group xml:lang="en"><kwd>major salivary glands</kwd><kwd>structure</kwd><kwd>sexual dimorphism</kwd><kwd>rodents</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>большие слюнные железы</kwd><kwd>строение</kwd><kwd>половой диморфизм</kwd><kwd>грызуны</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Афанасьев В. В., Зайратьянц О. В., Калинченко С. Ю., Степаненко Р. С. Взаимосвязь слюнных и половых желез. 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