<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Morphology</journal-id><journal-title-group><journal-title xml:lang="en">Morphology</journal-title><trans-title-group xml:lang="ru"><trans-title>Морфология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1026-3543</issn><issn publication-format="electronic">2949-2556</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">398860</article-id><article-id pub-id-type="doi">10.17816/morph.398860</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">THE PECULIARITIES OF UTERINE STRUCTURE AFTER DELIVERY IN RATS WITH THE MYOMETRIAL SCAR</article-title><trans-title-group xml:lang="ru"><trans-title>ОСОБЕННОСТИ СТРОЕНИЯ МАТКИ ПОСЛЕ РОДОВ У КРЫС С РУБЦОМ МИОМЕТРИЯ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Maiborodin</surname><given-names>I. V.</given-names></name><name xml:lang="ru"><surname>Майбородин</surname><given-names>Игорь Валентинович</given-names></name></name-alternatives><bio xml:lang="en"><p>Center of New Medical Technologies</p></bio><bio xml:lang="ru"><p>центр новых медицинских технологий</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pekarev</surname><given-names>O. G.</given-names></name><name xml:lang="ru"><surname>Пекарев</surname><given-names>Олег Григорьевич</given-names></name></name-alternatives><bio xml:lang="en"><p>Center of New Medical Technologies</p></bio><bio xml:lang="ru"><p>центр новых медицинских технологий</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Yakimova</surname><given-names>N. V.</given-names></name><name xml:lang="ru"><surname>Якимова</surname><given-names>Наталья Валентиновна</given-names></name></name-alternatives><bio xml:lang="en"><p>Center of New Medical Technologies</p></bio><bio xml:lang="ru"><p>центр новых медицинских технологий</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pekareva</surname><given-names>Ye. O.</given-names></name><name xml:lang="ru"><surname>Пекарева</surname><given-names>Евгения Олеговна</given-names></name></name-alternatives><bio xml:lang="en"><p>Center of New Medical Technologies</p></bio><bio xml:lang="ru"><p>центр новых медицинских технологий</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Maiborodina</surname><given-names>V. I.</given-names></name><name xml:lang="ru"><surname>Майбородина</surname><given-names>Виталина Игоревна</given-names></name></name-alternatives><bio xml:lang="en"><p>Center of New Medical Technologies</p></bio><bio xml:lang="ru"><p>центр новых медицинских технологий</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Perminova</surname><given-names>Ye. I.</given-names></name><name xml:lang="ru"><surname>Перминова</surname><given-names>Елена Игоревна</given-names></name></name-alternatives><bio xml:lang="en"><p>Center of New Medical Technologies</p></bio><bio xml:lang="ru"><p>центр новых медицинских технологий</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">RAS Siberian Branch Institute of Chemical Biology and Fundamental Medicine</institution></aff><aff><institution xml:lang="ru">Институт химической биологии и фундаментальной медицины СО РАН</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2015</year></pub-date><volume>147</volume><issue>2</issue><issue-title xml:lang="en">VOL 147, NO2 (2015)</issue-title><issue-title xml:lang="ru">ТОМ 147, №2 (2015)</issue-title><fpage>49</fpage><lpage>53</lpage><history><date date-type="received" iso-8601-date="2023-05-09"><day>09</day><month>05</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2015, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2015, Эко-Вектор</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://j-morphology.com/1026-3543/article/view/398860">https://j-morphology.com/1026-3543/article/view/398860</self-uri><abstract xml:lang="en"><p>The uterine tissues of female rats (n=30) with a scarred myometrium were examined by methods of light microscopy after the delivery. 1.5-2 months after the delivery no significant differences in the parameters of blood and lymph flow in the deep layers of the endometrium, myometrium and the myometrial scar tissue were found between the intact rats, nulliparous rats with a scarred uterus, rats that gave birth after laparotomy only and those that gave birth under the conditions of myometrial scar. In the course of pregnancy and labor activity, the damage of the tissues was observed not in the uterine scar proper, but at its borders with the myometrium. This is supported by the old hemorrhages and lymphostasis phenomena, greater number of lymphocytes, neutrophils, monocytes, macrophages and erythrocytes. In determining the indications and contraindications to vaginal childbirth in women with scarred uterus it is necessary to examine not only the scar proper, but also its border with the myometrium. The myometrial scar by itself, is not an absolute contraindication to vaginal delivery, the natural delivery is feasible in the absence of cavities with liquid and hemorrhages in the tissues of the uterine scar and at its border with myometrium.</p></abstract><trans-abstract xml:lang="ru"><p>Методами световой микроскопии исследовали ткани матки самок крыс (n=30) после родов с рубцом миометрия. Обнаружено, что через 1,5-2 мес после родов отсутствуют значимые различия показателей крово-и лимфотока в глубоких слоях эндометрия, миометрии и ткани рубца миометрия у интактных крыс, нерожавших с рубцом в матке, рожавших после лапаротомии и в условиях моделирования рубца миометрия. В процессе беременности и родовой деятельности происходит повреждение тканей не самого рубца матки, а пограничных с миометрием. Об этом свидетельствуют старые кровоизлияния и явления лимфостаза, большее число лимфоцитов, нейтрофилов, моноцитов, макрофагов и эритроцитов. При установлении показаний и противопоказаний к родам с рубцом в матке надо исследовать не только сам рубец, но и его границу с миометрием. Рубец в миометрии не является абсолютным противопоказанием к вагинальному родоразрешению, естественные роды при наличии рубца в матке допустимы при отсутствии полостей с жидкостью и геморрагий в тканях рубца в матке и на его границе с миометрием.</p></trans-abstract><kwd-group xml:lang="en"><kwd>uterine scar</kwd><kwd>hemorrhages</kwd><kwd>lymphatic cysts</kwd><kwd>uterus</kwd><kwd>delivery</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рубец миометрия</kwd><kwd>кровоизлияния</kwd><kwd>лимфатические кисты</kwd><kwd>матка</kwd><kwd>роды</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Лазаров Л., Стратиев С. Морфологична характеристика на цикатрикса при повторно цезарево сечение // Акуш. и гин. (София). 1993. Т. 32, № 2. С. 12-14.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Майбородин И. В., Домников А. В., Ковалевский К. П. Количество тучных клеток как индикатор ангиогенеза в аутотрансплантированных тканях // Морфология. 2003. Т. 124, вып. 6. С. 66-70.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Шехтер А. Б., Милованова З. П. Фибробласт-фиброкласт: Ультраструктурные механизмы резорбции коллагеновых волокон при инволюции соединительной ткани // Арх. пат. 1975. Т. 37, № 3. С. 13-19.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Якутина М. Ф. Сосуды и нервы шва матки после кесарева сечения (клинико-экспериментальное исследование // Вопр. охр. мат. 1968. Т. 13, № 6. С. 50-57.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Ben A. N., Sadfi A., Gara F. Advantages and risk of a trial of vaginal delivery in the scarred uterus // Tunis Med. 2003. Vol. 81, № 8. P. 563-566.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Diab A. E. Uterine ruptures in Yemen // Saudi Med. J. 2005. Vol. 26, № 2. P. 264-269.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Ezechi O. C., Mabayoje P., Obiesie L. O. Ruptured uterus in South Western Nigeria: a reappraisal // Singapore Med. J. 2004. Vol. 45, № 3. P. 113-116.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Hassan A. Trial of scar and vaginal birth after caesarean section // J. Ayub. Med. Coll. Abbottabad. 2005. Vol. 17, № 1. P. 57-61.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Head J. R., Seeling L. L. Jr. Lymphatic vessels in the uterine endometrium of virgin rats // J. Reprod. Immunol. 1984. Vol. 6, № 3. P. 157-166.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Kiss D., Gyorik J., Rajkovits K. Histological examination of uterus healing following cesarean section // Zbl. Gynäkol. 1978. Vol. 100, № 5. P. 309-312.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Klemm P., Koehler C., Mangler M. et al. Laparoscopic and vaginal repair of uterine scar dehiscence following cesarean section as detected by ultrasound // J. Perinat. Med. 2005. Vol. 33, № 4. P. 324-331.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Ofir K., Sheiner E., Levy A. et al. Uterine rupture: differences between a scarred and an unscarred uterus // Am. J. Obstet. Gynecol. 2004. Vol. 191, № 2. P. 425-429.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Scioscia M., Pontrelli G., Vimercati A. et al. A short-scheme protocol of gemeprost for midtrimester termination of pregnancy with uterine scar // Contraception. 2005. Vol. 71, № 3. P. 193- 196.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Singhal S. R., Agarwal U., Sangwan K. et al. Intrapartum posterior uterine wall rupture in lower segment cesarean section scarred uterus // Acta Obstet. Gynecol. Scand. 2005. Vol. 84, № 2. P. 196-197.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Uzoigwe S. A., Fiebai P. O., MacPepple D. A. Spontaneous midtrimester uterine rupture: a case report // Niger J. Med. 2004. Vol. 13, № 3. P. 290-292.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Yap O. W., Kim E. S., Laros R. K. Jr. Maternal and neonatal outcomes after uterine rupture in labor // Am. J. Obstet. Gynecol. 2001. Vol. 184, № 7. P. 1576-1581.</mixed-citation></ref></ref-list></back></article>
