MorphologyMorphologyМорфология1026-35432949-2556Eco-Vector39942310.17816/morph.399423ArticlesСтатьиOSTEOCYTIC BONE REMODELING: HISTORY OF THE PROBLEM, MORPHOLOGICAL MARKERSОСТЕОЦИТАРНОЕ РЕМОДЕЛИРОВАНИЕ КОСТНОЙ ТКАНИ: ИСТОРИЯ ВОПРОСА, МОРФОЛОГИЧЕСКИЕ МАРКЕРЫAvruninA SАврунинА С

Российский научно-исследовательский институт травматологии и ортопедии им. Р.Р. Вредена Росмедтехнологий

TikhilovR MТихиловР М

Российский научно-исследовательский институт травматологии и ортопедии им. Р.Р. Вредена Росмедтехнологий

AvruninA STykhilovR MРоссийский научно-исследовательский институт травматологии и ортопедии им. Р.Р. Вредена Росмедтехнологий150320111391NO1 (2011)№1 (2011)869409052023Copyright ©; 2011, Eco-VectorCopyright ©; 2011, Эко-Вектор2011Eco-VectorЭко-Векторhttps://j-morphology.com/1026-3543/article/view/399423

On the basis of the authors' own results and the analysis of the literature, the morphological markers of resorptive and synthetic phases of osteocytic bone remodeling under physiological conditions, are discussed. Their application by different authors is considered taking into account the history of the research of the osteocyte role in bone matrix metabolism (synthesis and resorption). Currently, there arose an urgent need for the quantitative assessment of osteocyte remodeling by combining routine histological methods of the osseous tissue study with the possibilities of modern image analysis systems.

На основании собственных данных и анализа литературы выделены морфологические маркеры резорбционной и синтетической фаз остеоцитарного ремоделирования в физиологических условиях. Их использование различными авторами рассмотрено с учетом истории исследования роли остеоцитов в обмене (синтез и резорбция) окружающего матрикса. В настоящее время возникла настоятельная необходимость проводить количественную оценку остеоцитарного ремоделирования, совмещая стандартные методы гистологического изучения костной ткани и современные возможности систем анализа изображений.

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