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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="obituary" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Morphology</journal-id><journal-title-group><journal-title xml:lang="en">Morphology</journal-title><trans-title-group xml:lang="ru"><trans-title>Морфология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1026-3543</issn><issn publication-format="electronic">2949-2556</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">629018</article-id><article-id pub-id-type="doi">10.17816/morph.629018</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Historical articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Исторические статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Personal</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Life and legacy of Yakov Lvovich Rapoport (on the 125th anniversary of his birth)</article-title><trans-title-group xml:lang="ru"><trans-title>Жизнь и научное наследие Якова Львовича Рапопорта: вклад в медицину (к 125-летию со дня рождения)</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Yakov L. Rapoport的生平和科学遗产 （在他出生的125周年纪念日）</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7147-7912</contrib-id><contrib-id contrib-id-type="spin">6975-6677</contrib-id><name-alternatives><name xml:lang="en"><surname>Mnikhovich</surname><given-names>Maxim V.</given-names></name><name xml:lang="ru"><surname>Мнихович</surname><given-names>Максим Валерьевич</given-names></name><name xml:lang="zh"><surname>Mnikhovich</surname><given-names>Maxim V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Medicine), Assistant Professor</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доцент</p></bio><bio xml:lang="zh"><p>Cand. Sci. (Medicine), Assistant Professor</p></bio><email>mnichmaxim@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1838-5802</contrib-id><contrib-id contrib-id-type="spin">7862-6199</contrib-id><name-alternatives><name xml:lang="en"><surname>Akhsanova</surname><given-names>Polina A.</given-names></name><name xml:lang="ru"><surname>Ахсанова</surname><given-names>Полина Алексеевна</given-names></name><name xml:lang="zh"><surname>Akhsanova</surname><given-names>Polina A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>doc.polina.tarasova@gmail.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5947-1523</contrib-id><contrib-id contrib-id-type="spin">3691-0148</contrib-id><name-alternatives><name xml:lang="en"><surname>Shiripenko</surname><given-names>Ivan A.</given-names></name><name xml:lang="ru"><surname>Ширипенко</surname><given-names>Иван Александрович</given-names></name><name xml:lang="zh"><surname>Shiripenko</surname><given-names>Ivan A.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>hikkiwahikki@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7792-1594</contrib-id><contrib-id contrib-id-type="spin">3943-4400</contrib-id><name-alternatives><name xml:lang="en"><surname>Bezuglova</surname><given-names>Tatyana V.</given-names></name><name xml:lang="ru"><surname>Безуглова</surname><given-names>Татьяна Васильевна</given-names></name><name xml:lang="zh"><surname>Bezuglova</surname><given-names>Tatyana V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Biology)</p></bio><bio xml:lang="ru"><p>канд. биол. наук</p></bio><bio xml:lang="zh"><p>Cand. Sci. (Biology)</p></bio><email>bezuglovat@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5851-2768</contrib-id><contrib-id contrib-id-type="spin">3230-3108</contrib-id><name-alternatives><name xml:lang="en"><surname>Procenko</surname><given-names>Dmitry D.</given-names></name><name xml:lang="ru"><surname>Проценко</surname><given-names>Дмитрий Дмитриевич</given-names></name><name xml:lang="zh"><surname>Procenko</surname><given-names>Dmitry D.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine), Assistant Professor</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доцент</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Medicine), Assistant Professor</p></bio><email>protsenko_d_d@staff.sechenov.ru</email><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1102-1133</contrib-id><contrib-id contrib-id-type="spin">1529-3528</contrib-id><name-alternatives><name xml:lang="en"><surname>Lozina</surname><given-names>Milena V.</given-names></name><name xml:lang="ru"><surname>Лозина</surname><given-names>Милена Владиславовна</given-names></name><name xml:lang="zh"><surname>Lozina</surname><given-names>Milena V.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>puzar.mila@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6704-9293</contrib-id><name-alternatives><name xml:lang="en"><surname>Gromov</surname><given-names>Pavel O.</given-names></name><name xml:lang="ru"><surname>Громов</surname><given-names>Павел Олегович</given-names></name><name xml:lang="zh"><surname>Gromov</surname><given-names>Pavel O.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>remol_dobronog@mail.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-1962-3020</contrib-id><name-alternatives><name xml:lang="en"><surname>Ostanin</surname><given-names>Oleg E.</given-names></name><name xml:lang="ru"><surname>Останин</surname><given-names>Олег Евгеньевич</given-names></name><name xml:lang="zh"><surname>Ostanin</surname><given-names>Oleg E.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>ostanin.oleg2011@yandex.ru</email><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Petrovsky National Research Centre of Surgery</institution></aff><aff><institution xml:lang="ru">Российский научный центр хирургии имени академика Б.В. Петровского</institution></aff><aff><institution xml:lang="zh">Petrovsky National Research Centre of Surgery</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Peoples' Friendship University of Russia named after Patrice Lumumba</institution></aff><aff><institution xml:lang="ru">Российский университет дружбы народов имени Патриса Лумумбы</institution></aff><aff><institution xml:lang="zh">Peoples' Friendship University of Russia named after Patrice Lumumba</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">N.I. Pirogov Russian National Research Medical University</institution></aff><aff><institution xml:lang="ru">Российский национальный исследовательский медицинский университет имени Н.И. Пирогова</institution></aff><aff><institution xml:lang="zh">N.I. Pirogov Russian National Research Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">The First Sechenov Moscow State Medical University (Sechenov University)</institution></aff><aff><institution xml:lang="ru">Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)</institution></aff><aff><institution xml:lang="zh">The First Sechenov Moscow State Medical University (Sechenov University)</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2024-07-24" publication-format="electronic"><day>24</day><month>07</month><year>2024</year></pub-date><pub-date date-type="pub" iso-8601-date="2024-09-04" publication-format="electronic"><day>04</day><month>09</month><year>2024</year></pub-date><volume>162</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>102</fpage><lpage>110</lpage><history><date date-type="received" iso-8601-date="2024-03-12"><day>12</day><month>03</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-06-26"><day>26</day><month>06</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Эко-Вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2024,</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2027-09-04"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0/</ali:license_ref></license></permissions><self-uri xlink:href="https://j-morphology.com/1026-3543/article/view/629018">https://j-morphology.com/1026-3543/article/view/629018</self-uri><abstract xml:lang="en"><p>2023 marks the 125<sup>th</sup> anniversary of the birth of Yakov Lvovich Rapoport, an outstanding Soviet pathologist, and professor who made a significant contribution to the development of medical science and left an important mark on literature and history with his frank memoirs about the “Doctors’ Plot” of 1953. The authors analyze the works of Ya.L. Rapoport, who devoted to the study of immunopathological processes in the human body, pathomorphosis, and two cardiomyopathies. The contribution of Ya.L. Rapoport to the development of new methods for diagnosing various diseases and the creation of advanced approaches to the study of pathological processes are described. Separately, the article describes the turning points in the scientist’s life. The early years of Ya.L. Rapoport’s life are interesting because of the choice between a creative career and medicine. In addition, his participation in the Great Patriotic War left a significant imprint on his life and career.</p></abstract><trans-abstract xml:lang="ru"><p>В 2023 году исполнилось 125 лет со дня рождения профессора Якова Львовича Рапопорта — выдающегося советского патологоанатома, внёсшего значительный вклад в развитие медицинской науки, а также оставившего важный след в литературе и истории откровенными мемуарами о «деле врачей» 1953 года. Проанализированы работы Я.Л. Рапопорта, посвящённые исследованию иммунопатологических процессов в организме человека, патоморфозу, а также кардиомиопатиям. Описан вклад Я.Л. Рапопорта в разработку новых методов диагностики различных заболеваний, а также в создание передовых подходов к изучению патологических процессов. Отдельно описаны переломные моменты жизни учёного: ранние годы жизни Якова Львовича Рапопорта интересны выбором между творческой карьерой и медициной; помимо этого, значимый отпечаток на его личную жизнь и карьеру наложило участие в Великой Отечественной войне.</p></trans-abstract><trans-abstract xml:lang="zh"><p>2023年是杰出的苏联病理学家Yakov L. Rapoport教授诞辰125周年，他为医学科学的发展做出了重大贡献，并通过他关于1953年的"医生案例"的坦率回忆录也在文学和历史上留下了重要的印记。</p> <p>Yakov L.Rapoport致力于研究人体免疫病理学过程，对病理形态以及心肌病的工作进行了分析。 描述了Yakov L. Rapoport对开发各种疾病的新诊断方法以及创建病理过程研究的先进方法的贡献。这位科学家生活的转折点被单独进行叙述：Yakov L. Rapoport生命的早年对于在创造性职业和医学之间进行选择很有趣。 此外，参加伟大的卫国战争在他的个人生活和职业生涯中留下了重要的印记。</p></trans-abstract><kwd-group xml:lang="en"><kwd>Yakov Lvovich Rapoport</kwd><kwd>pathological anatomy</kwd><kwd>history of medicine</kwd><kwd>the Doctors’ Plot</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Яков Львович Рапопорт</kwd><kwd>патологическая анатомия</kwd><kwd>история медицины</kwd><kwd>дело врачей</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>Yakov L. Rapoport</kwd><kwd>病理解剖学</kwd><kwd>医学史</kwd><kwd>医生案例</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Serov VV. Yakov Lvovich Rapoport (on the 100th anniversary of his birth). Russian Journal of Archive of Patology. 1998;60(4):53–54. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Серов В.В. Яков Львович Рапопорт (к 100-летию со дня рождения) // Архив патологии. 1998. Т. 60, № 4. С. 53–54.</mixed-citation><mixed-citation xml:lang="zh">Serov VV. Yakov Lvovich Rapoport (on the 100th anniversary of his birth). Russian Journal of Archive of Patology. 1998;60(4):53–54. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Rapoport NYa. Whether or not: of time and of self. Rostov-on-Don: Feniks; 2004. 396 p. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Рапопорт Н.Я. То ли быль, то ли небыль: о времени и о себе. Ростов-на-Дону: Феникс, 2004. 396 с.</mixed-citation><mixed-citation xml:lang="zh">Rapoport NYa. Whether or not: of time and of self. Rostov-on-Don: Feniks; 2004. 396 p. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">Rapoport NYa. About my father: on the tenth anniversary of his death. 2006. Available from: https://berkovich-zametki.com/2006/Zametki/Nomer1/Rapoport1.htm (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Рапопорт Н.Я. О моем отце: к десятой годовщине со дня смерти. 2006. Режим доступа: https://berkovich-zametki.com/2006/Zametki/Nomer1/Rapoport1.htm Дата обращения: 11.03.2024.</mixed-citation><mixed-citation xml:lang="zh">Rapoport NYa. About my father: on the tenth anniversary of his death. 2006. 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Moscow: Algoritm; 2017. 240. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Рапопорт Я.Л. «Дело врачей» 1953 года: показания обвиняемого. Москва: Алгоритм, 2017. 240 с.</mixed-citation><mixed-citation xml:lang="zh">Rapoport YaL. “Doctors’ case” 1953: testimony of the defendant. Moscow: Algoritm; 2017. 240. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">Burakovsky VI, Rapoport YaL, Gelshtein GG, et al. Complications of open heart surgery. Moscow: Mediczina; 1972. 342 p. (In Russ.). EDN: SKLXTX</mixed-citation><mixed-citation xml:lang="ru">Бураковский В.И., Рапопорт Я.Л., Гельштейн Г.Г., и др. Осложнения при операциях на открытом сердце. Москва: Медицина, 1972. 342 с. EDN: SKLXTX</mixed-citation><mixed-citation xml:lang="zh">Burakovsky VI, Rapoport YaL, Gelshtein GG, et al. Complications of open heart surgery. Moscow: Mediczina; 1972. 342 p. (In Russ.). 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