MorphologyMorphologyМорфология1026-35432949-2556Eco-Vector67895110.17816/morph.678951RMFWZRHistorical articlesИсторические статьиPersonalVladimir I. Nozdrin (1947–2024) and his contribution to Russian histologyВклад Владимира Ивановича Ноздрина (1947–2024) в развитие отечественной гистологииNozdrin（1947–2024）对俄罗斯组织学发展 的贡献https://orcid.org/0000-0001-9299-05716952-0466ShevlyukNicolai N.ШевлюкНиколай НиколаевичShevlyukNicolai N.
Russian Federation

Dr. Sci. (Biology), professor

доктор биологических наук, профессор

Dr. Sci. (Biology), professor

k_histology@orgma.ruhttps://elibrary.ru/author_profile.asp?authorid=97758Orenburg state medical universityОренбургский государственный медицинский университетOrenburg state medical university111020252512202516415152804202507062025Copyright ©; 2025, Eco-VectorCopyright ©; 2025, Эко-ВекторCopyright ©; 2025,2025Eco-VectorЭко-Векторhttps://eco-vector.com/for_authors.php#07https://j-morphology.com/1026-3543/article/view/678951

This article honors Professor Vladimir I. Nozdrin (1947–2024) and his significant contribution to Russian histology. Nozdrin was born on January 27, 1947, in the village of Olovyannikovo (now the village of Kalinino, Stanovo-Kolodez Rural Settlement) of the Oryol District, Oryol Region. After graduating from the Oryol Medical College (1965), he entered the I.M. Sechenov First Moscow Medical Institute, from which he graduated in 1971. Following graduation, Nozdrin worked at various universities and research institutes in Moscow. Later, he founded the Department of Histology, Cytology, and Embryology at the Medical Institute of Oryol University, serving as its head from 1999 to 2020. Under his supervision, the department became one of the leading histology departments. From 1991 to 2016, Nozdrin also headed the pharmaceutical enterprise Retinoids JSC, which repeatedly received the Leader of the Russian Economy award. His primary research area was skin histophysiology. He investigated embryonic and postnatal morphogenesis of skin structures and their derivatives, establishing the patterns of their age-related transformations. Nozdrin investigated adaptive and reactive transformations of skin structures induced by various pharmaceuticals, as well as the biological properties of retinoids, their role in the body, and their potential for optimizing reparative histogenesis in the skin. Nozdrin devoted considerable attention to teaching histology. Together with co-authors, he prepared a series of textbooks and manuals on histology, cytology, and embryology, which were highly praised by both students and faculty. Nozdrin successfully worked on preserving the historical memory of prominent Russian and Soviet histologists, such as Babukhin, Eliseev, and Afanasyev. Of particular note is his work in organizing scientific conferences, including the Babukhin Readings in Oryol (10 conferences between 2002 and 2017), the 8th Congress of the International Association of Morphologists (2006), and several others. These events brought together leading morphologists from Russia and the CIS, as well as young researchers for whom such prestigious conferences became an invaluable professional experience. Professor Nozdrin made a significant contribution to the progress of cell biology, tissue biology, and embryology.

Статья посвящена профессору Владимиру Ивановичу Ноздрину (1947–2024) и его вкладу в развитие отечественной гистологии. Владимир Иванович родился 27 января 1947 года в деревне Оловянниково (ныне село Калинино Станово-Колодезьского сельского поселения) Орловского района Орловской области. После окончания Орловского медицинского училища (в 1965 году) он поступил в Первый Московский медицинский институт имени И.М. Сеченова, который окончил в 1971 году. После окончания института В.И. Ноздрин работал в вузах и научно-исследовательских институтах Москвы. Позже, Владимир Иванович создал в Медицинском институте Орловского университета кафедру гистологии, цитологии и эмбриологии, которой заведовал с 1999 по 2020 год. Под его руководством кафедра вошла в число лучших кафедр гистологии. С 1991 по 2016 год В.И. Ноздрин также возглавлял основанное им фармацевтическое предприятие ЗАО «Ретиноиды», которое неоднократно становилось победителем в номинации «Лидер экономики России». Основные научные исследования Владимира Ивановича посвящены вопросам гистофизиологии кожи. Им изучены процессы эмбрионального и постнатального морфогенеза структур кожи и её производных, установлены закономерности их возрастных преобразований. В.И. Ноздрин успешно разрабатывал вопросы адаптивных и реактивных преобразований структурных элементов кожи в условиях действия различных фармпрепаратов, занимался исследованием биологических свойств ретиноидов, их роли и значимости в организме, а также в оптимизации репаративных гистогенезов в коже. Много внимания В.И. Ноздрин уделял вопросам преподавания гистологии. Им (в соавторстве) подготовлен ряд учебных пособий по гистологии, цитологии и эмбриологии, которые получили высокую оценку студентов и преподавателей. Владимир Иванович успешно занимался вопросами сохранения исторической памяти о видных российских и советских гистологах — А.И. Бабухине, В.Г. Елисееве, Ю.И. Афанасьеве. Особо следует отметить деятельность В.И. Ноздрина, связанную с организацией научных конференций: «Бабухинские чтения в Орле» (10 конференций в период с 2002 по 2017 год), VIII конгресс Международной ассоциации морфологов (2006) и ряд других. В работе этих конференции участвовали как ведущие морфологи России и стран СНГ, так и молодые учёные, для которых такие представительные конференции стали хорошей школой. Таким образом, деятельность Владимира Ивановича Ноздрина, несомненно, способствовала прогрессу клеточной биологии, биологии тканей и эмбриологии.

本文纪念俄罗斯著名组织学家、教育家、生物学博士、教授Vladimir I. Nozdrin（1947–2024），并介绍其在俄罗斯组织学发展中的重要贡献。1947年1月27日，Nozdrin出生于Oryol州Oryol区Olovyannikovo村（今Kalinino, Stanovo-Kolodez Rural Settlement村）。1965年毕业于奥廖尔医学院，1971年毕业于以I.M. Sechenov First Moscow Medical Institute。毕业后，Nozdrin先后在莫斯科多所高等院校和科研机构从事教学与科研工作。随后，Nozdrin教授在Oryol University医学院创立了组织学、细胞学与胚胎学教研室，并于1999年至2020年任系主任，使该教研室跻身俄罗斯组织学领域的领先学术中心。1991年至2016年，他还领导自己创办的制药企业JSC “Retinoids”，该企业多次荣获《俄罗斯经济领军者》称号。Nozdrin教授的主要科学研究集中于皮肤组织生理学领域。他系统研究了皮肤及其附属结构在胚胎期与出生后期的形态发生过程，揭示了其年龄相关的结构重塑规律。Nozdrin深入研究了不同药物作用下皮肤结构要素的适应性和反应性变化，探讨了视黄醇类物质（retinoids）的生物学特性及其在机体中的作用，并阐明了其在皮肤修复性组织发生优化过程中的重要意义。在教学方面，Nozdrin教授高度重视组织学教育工作。他（与同事合著）编写了多部组织学、细胞学与胚胎学教材，广受师生好评。Nozdrin还积极推动对俄罗斯与苏联杰出组织学家Babukhin, Eliseev和Afanasyev的学术传承与历史记忆的保存。特别值得指出的是，Nozdrin教授在组织学术会议方面的工作，包括在“Babukhin Readings in Oryol”（2002–2017年共10届）、第八届国际形态学家协会大会（2006年）及其他会议。来自俄罗斯及独联体国家的知名形态学家和青年学者广泛参与，这些会议成为青年科研人员的重要学术平台。Nozdrin的科学与教育事业无疑促进了细胞生物学、组织生物学与胚胎学的发展。

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(In Russ.)Zhuchkov SA, Belousova TA, Nozdrin VI. Epidermal thickness and keratinocyte proliferation after cutaneous application of vitamin D3. Morphology. 2012;142(6):56–60. EDN: PJDQUVNozdrin VI, Gorelova MV, Belousova TA. Age-related changes of the epidermis of men’s scalp. Morphology. 2011;139(1):74–81. EDN: NCPAEFAlekseyev AG, Banin VV, Nozdrin VI. Skin melanocytes. Morphology. 2009;136(5):81–89. EDN: KYNLFBNozdrin VI, Alekseyev AG. Melanocytes of the epidermis and hair follicles in men in ontogenesis. Moscow: ZAO «Retinoidy»; 2012. (In Russ.) ISBN: 978-5-93118-036-6 EDN: QKUZBHNozdrin VI, Alekseyev AG, Belousova TA. Age-related characteristics of melanocytes in the hair follicles of the temporal region skin in men. Morphology. 2011;139(3):67–72. EDN: NYODGJGorpinich IV, Nozdrin VI. Morpho-functional changes of hair during their renewal. Morphology. 2007;132(5):7–17. EDN: IJDWEDNozdrin VI, Belousova TA, Trunova GV. Age-related dynamics of the representation of hair change cycle stages in the skin of the human scalp. Morphology. 2016;149(3):151. (In Russ.) EDN: WJIUOBTrunova GV, Nozdrin VI. Methods of morphological identification of the hair follicle cycle phases. Morphology. 2016;149(2):77–84. EDN: TQNXXPKalinina OV, Belousova TA, Nozdrin VI. Age peculiarities of the sebaceous glands in the temporal area of the scalp skin in men. Morphology. 2013;143(2):69–74. EDN: PZIFSNNozdrin VI, Kalinina OV. The skin sebaceous glands of temporal region of men head in postnatal ontogenesis. Astrakhan Medical Journal. 2012;7(4):200–202. EDN: PWTDFZNozdrin VI, Polyachenko LN, Volkov YuT. Experimental study of the effect of 13-cis-retinoic acid (13cRA) on sebaceous glands. In: Almanac «Retinoids». Moscow: ZAO «Retinoidy»; 1997. P:29–32. (In Russ.)Kostyaeva MG, Bykova EV, Andreeva VV, et al. Effect of Radevit-active ointment on atrophic changes caused by application of ointment with glucocorticosteroids. 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