EFFECT OF RADIATION STERILIZATION ON BIOMATERIAL STRUCTURE AND PROPERTIES
- 作者: Shangina OR1, Nigmatullin RT1
-
隶属关系:
- All-Russian Center of Eye and Plastic Surgery, Ufa
- 期: 卷 129, 编号 3 (2006)
- 页面: 44-47
- 栏目: Articles
- ##submission.dateSubmitted##: 09.05.2023
- ##submission.datePublished##: 15.09.2006
- URL: https://j-morphology.com/1026-3543/article/view/398990
- DOI: https://doi.org/10.17816/morph.398990
- ID: 398990
如何引用文章
详细
The purpose of the investigation was the study of structural changes connective tissue biomaterials after different combinations of their radiation sterilization, physico-chemical treatment and conservation. Using a complex of histological methods (polarization microscopy of unstained sections, van Gieson's stain, scanning electron microscopy), an analysis was performed to detect the structural changes in tendons and dermis which underwent various physico-chemical treatment and subjected to the radiation sterilization using different types (з- radiation and fast-moving electron stream) and doses (1.5, 2.5 and 4 Mrad) of radiation. The dependence of the structural changes in the biomaterials on the fibroarchitectonics of the tissue as well as on the physico-chemical treatment and radiation type and dose was demonstrated. The tendons underwent clear-cut significant changes in all regimes and radiation doses studied. Dermis was found to be most resistant to radiation challenge.
作者简介
O Shangina
All-Russian Center of Eye and Plastic Surgery, Ufa
Email: alloOlga@mail.ru <mailto:alloOlga@mail.ru>
All-Russian Center of Eye and Plastic Surgery, Ufa
R Nigmatullin
All-Russian Center of Eye and Plastic Surgery, Ufa
Email: nigmatullinr@mail.ru <mailto:nigmatullinr@mail.ru>
All-Russian Center of Eye and Plastic Surgery, Ufa
参考
- Лекишвили М.В. Варианты деминерализованных костных аллоимплантатов для использования в восстановительной хирургии. В кн.: Клинические и фундаментальные аспекты клеточных и тканевых биотехнологий. Самара, Офорт, 2004, с. 92-94.
- Лекишвили М.В., Исаева Е.И., Пономарев В.Н. и Васильев М.Г. Лучевая стерилизация деминерализованных костных трансплантатов в свете профилактики инфицирования гепатитом В и С. Вестн. травматол. и ортопед., 2002, № 1, с. 75-77.
- Нигматуллин Р.Т. Очерки трансплантации тканей. Уфа, ООО Ксерокс СТМ, 2003.
- Савельев В.И., Корнилов Н.В. и Калинин А.В. Актуальные проблемы трансплантации тканей. СПб., МОРСАР АВ, 2001.
- Сорокин А.П. Общие закономерности строения опорного аппарата человека. М., Медицина, 1973.
- Pruss A., Baumann B., Seibold M. et al. Validation of sterilization procedure of allogenic avital bone transplants using peracetic acid-ethanol. Biological, 2001, v. 29, p. 59-66.
- Pruss A., Kao M., Gohs U. et al. Effect of gamma irradiation on human cortical bone transplants contaminated with enveloped and non-enveloped viruses. Biological, 2002, v. 30, p. 125-133.
- Salehpour A., Butler D.L., Proch F.S. et al. Dose-dependent response of gamma irradiation on mechanical properties and relatied biochemical composition of goat bone-patellar tendon-bone allografts. Orthop. Res., 1995, v. 13, № 6, p. 898-906.
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