COMPUTER ASSESSMENT OF MEMBRANESTRUCTURE IN VARIOUS ERYTHROCYTEFORMS



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The photometric computer image analysis method is described.
It is based on the creation of the gallery of the images of various
erythrocyte forms (discocytes, ecchinocytes, target cells and degenerative forms). Using the Bio Vision program, the structure
of membranes of each type of erythrocytes was studied. It was found that the morpho-functional changes of erythrocytes of various
degrees were accompanied by the alterations in the relative
content of condensed membrane protein-lipid complexes.

作者简介

M Lutsenko

M Lutsenko

Far Eastern Center of RespiratoryPhysiology and Pathology, RAMS SB

Far Eastern Center of RespiratoryPhysiology and Pathology, RAMS SB

参考

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  2. Рябов С.И. и Шостка Г.Д. Молекулярно-генетические аспекты эритропоэза. Л., Медицина, 1973.
  3. Branton D., Cohen C.M. and Tyler J. Interaction of cytoskeletal proteins on the human erythrocyte membrane. Cell, 1981, v. 24, p. 24-32.
  4. Snyder L.M., Leb L., Piotrowski J. et al. Irreversible spectrinhemoglobin crosslinking in vivo: a marker for red cell senescence.
  5. Brit. J. Haematol., 1983, v. 53, № 3, p. 379-384.
  6. Steck T.L. The organization of proteins in human red blood cell membrane. J. Cell. Biol., 1974, v. 62, p. 1-19.

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