PATHOGENIC PROPERTIES OF GENETICALLY MODIFIED MICROORGANISM ASSESSMENT AS ONE OF THE CRITERIA OF BIOSAFETY
- Authors: Sheina N.I.1
-
Affiliations:
- N.I. Pirogov Russian National Research Medical University, 1, Ostrovitaynova str. Moscow
- Issue: Vol 96, No 3 (2017)
- Pages: 284-286
- Section: EXPERIMENTAL INVESTIGATIONS
- Published: 21.10.2020
- URL: https://j-morphology.com/0016-9900/article/view/640641
- DOI: https://doi.org/10.47470/0016-9900-2017-96-3-284-286
- ID: 640641
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Abstract
In the experiment there were studied pathogenic properties of the 10 genetically-modified E.coli strains and S. cerevisiae in terms of virulence, toxicity and toxigenicity, invasiveness and ability to the dissemination. Most of studied strains were shown to have no pathogenic properties and be able therefore to be recommended for the use in biotechnology. Along with this 2 strain of E.coli DLT1270 2 and E.coli ECR-HIS-T had a highly invasive properties and therefore can be a dangerous for warm-blooded animals and humans.
About the authors
N. I. Sheina
N.I. Pirogov Russian National Research Medical University, 1, Ostrovitaynova str. Moscow
Author for correspondence.
Email: ni_sheina@mail.ru
Russian Federation
References
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