Email this article Targeting Cysteine and Serine Proteases to Discover New Drugs Against Neglected Tropical Diseases
- Authors: dos Santos Nascimento I.1, de Moura R.2
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Affiliations:
- Programa de Pós-graduação em Ciências Farmacêuticas ,, Universidade Estadual da Paraíba
- Programa de Pós-graduação em Ciências Farmacêuticas,, Universidade Estadual da Paraíba
- Issue: Vol 31, No 16 (2024)
- Pages: 2133-2134
- Section: Anti-Infectives and Infectious Diseases
- URL: https://j-morphology.com/0929-8673/article/view/644434
- DOI: https://doi.org/10.2174/092986733116240214143511
- ID: 644434
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About the authors
Igor dos Santos Nascimento
Programa de Pós-graduação em Ciências Farmacêuticas ,, Universidade Estadual da Paraíba
Email: info@benthamscience.net
Ricardo de Moura
Programa de Pós-graduação em Ciências Farmacêuticas,, Universidade Estadual da Paraíba
Email: info@benthamscience.net
References
- Nascimento, I.J. dos S.; Cavalcanti, M. de A.T.; de Moura, R.O. Exploring N-myristoyltransferase as a promising drug target against parasitic neglected tropical diseases. Eur. J. Med. Chem., 2023, 258, 115550.
- De Souza, M.; Medeiros, D.C.; de Moura, R.O.; dos Santos Nascimento, I.J. Pharmacokinetic limitations to overcome and enable K777 as a potential drug against chagas disease. Curr. Pharm. Des., 2023, 29, 2359-2360.
- dos Santos Nascimento, I.J.; de Aquino, T.M.; da Silva-Júnior, E.F. Cruzain and rhodesain inhibitors: last decade of advances in seeking for new compounds against American and African trypanosomiases. Curr. Top. Med. Chem., 2021, 21, 1871-1899.
- dos Santos Nascimento, I.J.; da Silva Rodrigues, É.E.; da Silva, M.F.; de Araújo-Júnior, J.X.; de Moura, R.O. Advances in computational methods to discover new NS2B-NS3 inhibitors useful against dengue and zika viruses. Curr. Top. Med. Chem., 2022, 22, 2435-2462.
- Saha, A. Pushpa; Moitra, S.; Basak, D.; Brahma, S.; Mondal, D.; Molla, S.H.; Samadder, A.; Nandi, S. Targeting cysteine proteases and their inhibitors to combat trypanosomiasis. Curr. Med. Chem., 2024, 31(16), 2135-2169.
- Giroud, M.; Kuhn, B.; Haap, W. Drug discovery efforts to identify novel treatments for neglected tropical diseases - cysteine protease inhibitors. Curr. Med. Chem., 2024, 31(16), 2170-2194.
- Akram, M.; Hameed, S.; Hassan, A.; Khan, K. Development in the inhibition of dengue proteases as drug targets. Curr. Med. Chem., 2024, 31(16), 2195-2233.
- Hernández González, J.E.; Salas-Sarduy, E.; Alvarez, L.H.; Valiente, P.A.; Arni, R.K.; Pascutti, P.G. Three decades targeting falcipains to develop antiplasmodial agents: What have we learned and what can be done next? Curr. Med. Chem., 2024, 31(16), 2234-2263.
- Nascimento, I.; Albino, S.; Menezes, K.; Cavalcanti, M.; Oliveira, M.; Mali, S.; Moura, R. Targeting SmCB1: Perspectives and insights to design antischistosomal drugs. Curr. Med. Chem., 2024, 31(16), 2264-2284.
- Prates, J.L.B.; Lopes, J.R.; Chin, C.M.; Ferreira, E.I.; dos Santos, J.L.; Scarim, C.B. Discovery of novel inhibitors of cruzain cysteine protease of Trypanosoma cruz. Curr. Med. Chem., 2024, 31(16), 2285-2308.
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