BELOK KLETOChNYKh KONTAKTOV BETA-KATENIN V KLETKAKh EPENDIMY I EPITELIYa SOSUDISTOGO SPLETENIYa BOKOVYKh ZhELUDOChKOV GOLOVNOGO MOZGA



Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The purpose of this study was to examine the distribution pattern of cellular contacts protein beta-catenin in the choroid plexus and ependyma of lateral ventricles of the brain. The study was conducted on frontal sections of the brain of Wistar rats (n=10) using polyclonal antibodies against beta-catenin. The obtained preparations were analyzed by microscopy in transmitted light and using confocal laser microscopy. To study the distribution of beta-catenin in different projections, three-dimensional reconstruction was performed. The study demonstrated different distribution patterns of this protein in ependyma and choroid plexus. Unlike ependyma, in the cells of the choroid plexus beta-catenin was distributed in the same way as in simple epithelial tissues (on the basal and lateral borders of the cells). This may indicate different tissue attribution of the ependyma and the choroid plexus epithelium, despite their common origin.

Full Text

Restricted Access

About the authors

O. V. Kirik

RAS Research Institute of Experimental Medicine

Laboratory of Functional Morphology of the Central and Peripheral Nervous System, Department of General and Special Morphology

D. A. Sufieyva

RAS Research Institute of Experimental Medicine

Email: rondo-13@mail.ru
Laboratory of Functional Morphology of the Central and Peripheral Nervous System, Department of General and Special Morphology

A. V. Nazarenkova

RAS Research Institute of Experimental Medicine

Email: phucus@mail.ru
Laboratory of Functional Morphology of the Central and Peripheral Nervous System, Department of General and Special Morphology

D. E. Korzhevskiy

RAS Research Institute of Experimental Medicine; St. Petersburg State University

Email: iemmorphol@yandex.ru
Laboratory of Functional Morphology of the Central and Peripheral Nervous System, Department of General and Special Morphology; Department of Fundamental Problems of Medicine and Medical Technology

References

  1. Кирик О. В., Суфиева Д. А., Назаренкова А. В., Коржевский Д. Э. Структурная организация отростков эпендимоцитов, образующих выстилку боковых желудочков головного мозга // Морфология, 2015. Т. 147, вып. 2. С. 17-21.
  2. Коржевский Д. Э. Эпителий сосудистого сплетения // Руководство по гистологии. Т. 1. СПб.: СпецЛит, 2001. С. 177- 179.
  3. Коржевский Д. Э., Сухорукова Е. Г., Гилерович Е. Г. и др. Преимущества и недостатки цинк-этанол-формальдегида как фиксатора для иммуноцитохимических исследований и конфокальной лазерной микроскопии // Морфология. 2013. Т. 143, вып. 2. С. 81-85.
  4. Международные термины по цитологии и гистологии человека с официальным списком русских эквивалентов / Под ред. В. В. Банина, В. Л. Быкова. М.: ГЭОТАР-Медиа, 2009.
  5. Giachino C., Basak O., Lugert S. et al. Molecular diversity subdivides the adult forebrain neural stem cell population // Stem. Cells. 2014. Vol. 32, № 1. P. 70-84.
  6. Meeker R. B., Bragg D. C., Poulton W., Hudson L. Trans migration of macrophages across the choroid plexus epithelium in response of the feline immunodeficiency virus // Cell Tiss. Res. 2012. Vol. 347, № 2. P. 443-455.
  7. Nürnberger J., Feldkamp T., Kavapurackal R. et al. N-cadherin is depleted from proximal tubules in experimental and human acute kidney injury // Histochem. Cell Biol. 2010. Vol. 133, № 6. P. 641-649.
  8. Tyler S. Epithelium. The primary building block for metazoan complexity // Integr. Comp. Biol. 2003. Vol. 43. P. 55-63.
  9. Valenta T., Hausmann G., Basler K. The many faces and functions of в-catenin // EMBO J. 2012. Vol. 31. P. 2714-2736.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2016 Eco-Vector


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: № 0110212 от 08.02.1993.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies