EFFECT OF TOTAL SIALOADENECTOMY ON THE STRUCTURE OF RAT TESTIS



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Abstract

The effect of the major salivary gland removal on the structure of the testes was studied in immature (n=120) and adult (n=120) rats. Testes of intact (n=40), sham-operated (n=40) and sialoadenectomized (n=40) animals were examined at weeks 1, 2, 3, 4, 6, 8, 10 and 12 of the experiment by histological and morphometric methods. In the early stages (up to 6 weeks) after total sialoadenectomy, the multinucleated spermatids and dying cells were observed in the seminiferous epithelium. The diameter of the convoluted seminiferous tubules and spermatogenesis index were decreased. These changes were more pronounced but sooner leveled in mature rats.

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About the authors

V. V. Ivanova

Siberian State Medical University

Email: ivvera92@rambler.ru
Department of Morphology and General Pathology

I. V. Mil’to

Siberian State Medical University; Tomsk National Research Polytechnic University

Department of Morphology and General Pathology; Department of Biotechnology and Organic Chemistry

I. V. Sukhodolo

Siberian State Medical University

Department of Morphology and General Pathology

A. S. Buyankina

Tomsk National Research Polytechnic University

Department of Biotechnology and Organic Chemistry

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