MORPHOMETRIC ANALYSIS OF BLOOD VESSELS OF TIBIAL REGENERATE IN TIBIA AUTOMATIC LENGTHENING AT AN INCREASED RATE

Objective - to study the characteristics of blood supply of the distraction regenerate of the tibia at different stages of the automatic lengthening of the tibia at increased rate. Materials and methods. Blood vessels of the tibia were studied in 25 adult mongrel dogs, in 15 of which the shin was lengthened by the method of transosseous distraction osteosynthesis with the use of automatic actuators at the rate of 3 mm/day and high frequency mode. Blood vessel numerical density and diameters were determined in the distraction regenerate at different stages of osteogenesis and in bones of intact animals. Results. After the injury, vasodilation of veins, arterial hypotonia, reduced numerical density of arterial and venous type blood vessels were observed. Repair processes were accompanied by 2.0-3.7-fold increase in the number of capillaries in the different areas of the regenerate, the contraction of arterioles and expansion of the capillaries and venules. In the period of fixation of the bone, changes in the larger vessels were less pronounced than in the microcirculatory vessels. Increase in the daily rate of tibia lengthening up to 3 mm, while reducing the overall hardware period by 30-31% did not disturb the adaptation of the vasculature to the terms of the elongation. Conclusions. The method of transosseous distraction osteosynthesis with the proposed rate of tibia lengthening does not violate the microcirculation in the bone regenerate and is optimal for osteogenesis.

tibial bone, blood vessels, distraction osteosynthesis, morphometric parameters