SUBEPENDYMAL MICROGLIOCYTES OF THE THIRD VENTRICLE OF THE BRAIN
- 作者: Kirik O.V.1, Sukhorukova Y.G.1, Alekseyeva O.S.1, Korzhevskiy D.E.1
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隶属关系:
- RAMS North-Western Branch Institute of Experimental Medicine
- 期: 卷 145, 编号 2 (2014)
- 页面: 67-69
- 栏目: Articles
- ##submission.dateSubmitted##: 09.05.2023
- ##submission.datePublished##: 15.04.2014
- URL: https://j-morphology.com/1026-3543/article/view/398761
- DOI: https://doi.org/10.17816/morph.398761
- ID: 398761
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详细
The goal of the study was to identify the subependymal microglial cells of the III ventricle of the rat brain and to determine their structural characteristics. The sections of the brain of intact Wistar (n=3) and Sprague-Dawley (n=3) male rats were studied using the methods of immunocytochemistry and confocal laser microscopy. Subependymal microglia of the III ventricle was found to be a constantly present cell population. Two types of subependymal microgliocytes were identified - spindle-like and basket cells. Their processes penetrate the ependymal layer and reach its surface, thus contacting the cerebrospinal fluid (CSF), which suggests a possible participation of these cells in the structure of CSF-brain barrier.
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作者简介
O. Kirik
RAMS North-Western Branch Institute of Experimental Medicine
Email: olga_kirik@mail.ru
Ye. Sukhorukova
RAMS North-Western Branch Institute of Experimental Medicine
Email: len48@inbox.ru
O. Alekseyeva
RAMS North-Western Branch Institute of Experimental Medicine
Email: osa72@inbox.ru
D. Korzhevskiy
RAMS North-Western Branch Institute of Experimental Medicine
Email: iemmorphol@yandex.ru
参考
- Кирик О. В., Сухорукова Е. Г. и Коржевский Д. Э. Кальцийсвязывающий белок Iba-1/AIF-1 в клетках головного мозга крысы. Морфология, 2010, т. 137, вып. 2, с. 5-8.
- Коржевский Д. Э., Кирик О. В., Сухорукова Е. Г. и Власов Т. Д. Структурная организация микроглиоцитов стриатума после транзиторной фокальной ишемии. Морфология, 2012, т. 141, вып. 2, с. 28-32.
- Хожай Л. И. и Отеллин В. А. Реактивные изменения микроглии в неокортексе и гиппокампе у крыс после воздействия острой перинатальной гипоксии. Морфология, 2013, т. 143, вып. 1, с. 23-27.
- Davis E. J., Foster T. D. and Thomas W. E. Cellular forms and functions of brain microglia. Brain Res. Bull., 1994, v. 4, № 1, р. 73-78.
- Graeber M. B. and Streit W. J. Microglia: biology and pathology. Acta Neuropathol., 2010, v. 119, р. 89-105.
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