Email this article THE DYNAMICS OF QUANTITATIVE PARAMETERS OF RAT ADRENAL MEDULLA AFTER ITS PARTIAL LASER DESTRUCTION
- Authors: Kemoklidze K.G.1, Tiumina N.A.1
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Affiliations:
- Yaroslavl’ State Medical Academy
- Issue: Vol 146, No 6 (2014)
- Pages: 63-67
- Section: Articles
- URL: https://j-morphology.com/1026-3543/article/view/398833
- DOI: https://doi.org/10.17816/morph.398833
- ID: 398833
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Abstract
Morphometric methods were used to examine the dynamics of the quantitative parameters of the surviving portion of the adrenal medulla (AM) in Wistar rats (n=41) for 2 months after its laser damage. On paraffin sections of AM stained using L. H. Honore method, the volume fractions and the average cross-sectional areas of adrenalocytes and noradrenalocytes as well as the volume fractions of blood vessels, stroma and neurons were determined. The relative volume of the blood vessels reached its maximum value at Day 7, and that of the chromaffinocytes - at Day 28 of the experiment. The volume fractions of the stroma and neurons demonstrated no significant changes during the experiment. The original method was used to calculate the real decrease and increase in the volume of glandular parenchyma of the surviving portion of AM. The real decline of chromaffinocyte volume reached a maximum of 1.5% at Day 7, and the maximum real growth of 4.7% was observed at Day 28 (the growth rate amounted to 1-2.5% per week). Until Day 28 chromaffinocyte hyperplasia dominated in the regenerative processes, while on Day 28 the hypertrophy was also found to significantly contribute to it. By Day 56 the surviving zone of AM was normalized.
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About the authors
K. G. Kemoklidze
Yaroslavl’ State Medical Academy
Email: K_G_K@mail.ru
N. A. Tiumina
Yaroslavl’ State Medical Academy
Email: Natellamail@mai.ru
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).