Email this article EXTRUSION OF THE TRACHEAL EPITHELIAL CELLS (IN VIVO STUDY)
- Authors: Yesev L.I.1, Pavlov A.V.1
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Affiliations:
- Yaroslavl’ State Medical Academy
- Issue: Vol 146, No 6 (2014)
- Pages: 87-90
- Section: Articles
- URL: https://j-morphology.com/1026-3543/article/view/398845
- DOI: https://doi.org/10.17816/morph.398845
- ID: 398845
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Abstract
Using a complex technique of intravital microscopic study, the epithelial lining of the trachea of 35 albino male Wistar rats aged 3 ,6, 12, 18 and 24 months was examined in combination with its histological study. During the analysis of video files of the ciliary apparatus motor activity, a phenomenon of epithelial cell extrusion from the cell layer was registered and the main phases of this process were described (the appearance of the apical part of the cell being eliminated above the epithelial surface, the release of its nucleated part, the final release of the cell from the layer). It was found that not only the dying cells were extruded, but also the viable elements, preserving the ciliary activity and unchanged morphological structure of nuclei (up to 25% of the total number of eliminated cells). The study of the histological sections demonstrated the ciliated cells at the respective stages of the extrusion process. The total proportion of the epithelial cells being eliminated was 0.4-0.6‰ in young animals (3- 6 months old), while in adult and aging rats (12-24 months old) it was equal to 0.9-1.1‰.
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About the authors
L. I. Yesev
Yaroslavl’ State Medical Academy
A. V. Pavlov
Yaroslavl’ State Medical Academy
Email: pavlov@yma.ac.ru
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Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).