MORPHO-FUNCTIONAL PARAMETERS OF CORPUS LUTEUM IN NORMAL WOMEN AND IN PATIENTS WITH UTERINE MYOMA



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Abstract

Ovarian corpus luteum of menstruation at the stage of its peak activity was studied in normal women and in patients with proliferative uterine myoma using ultrasonography (intravaginal color doppler imaging), laboratory analyses (progesterone and estrogen concentrations in peripheral blood) and morphological (histological, histochemical and morphometric) methods. In patients with proliferative uterine myoma, the defective corpus luteum was detected, as indicated by the prevalence of small granulosa lutein cells, insignificant amount and uneven distribution of lipid inclusions in their cytoplasm, marked reduction of progesterone concentration in peripheral blood, unechogenicity, low degree of vascularization and increase in the value of resistance index of ovarian stromal arteries.

About the authors

G S Daneliya

M B Paylodze

M A Dgebuadze

Email: illusion_ia2001@yahoo.com <mailto:illusion_ia2001@yahoo.com>

S G Matitashvili

G S Danelia

K.V. Chachava Institute of Perinatal Medicine,Tbilisi State Medical University

; K.V. Chachava Institute of Perinatal Medicine,Tbilisi State Medical University

M V Pailodze

K.V. Chachava Institute of Perinatal Medicine,Tbilisi State Medical University

; K.V. Chachava Institute of Perinatal Medicine,Tbilisi State Medical University

M A Dgebuadze

K.V. Chachava Institute of Perinatal Medicine,Tbilisi State Medical University

; K.V. Chachava Institute of Perinatal Medicine,Tbilisi State Medical University

S G Matitashvili

K.V. Chachava Institute of Perinatal Medicine,Tbilisi State Medical University

; K.V. Chachava Institute of Perinatal Medicine,Tbilisi State Medical University

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