Email this article Parasympathetic innervation of proximal parts of the colon in cat
- Authors: DOROFEYEVA AA1, PANTELEYEV SS1, MAKAROV FN1
-
Affiliations:
- RAS L.P. Pavlov Institute of Physiology
- Issue: Vol 132, No 6 (2007)
- Pages: 34-38
- Section: Articles
- URL: https://j-morphology.com/1026-3543/article/view/399041
- DOI: https://doi.org/10.17816/morph.399041
- ID: 399041
Cite item
Open Access
Access granted
Subscription or Fee Access
Abstract
The localization and morphometric features of efferent para-sympathetic neurons of the vagus dorsal motor nucleus and of the spinal sacral parasympathetic nucleus innervating
the area of ileocaecal sphincter, ascending and transverse colon, were investigated. In urethane anaesthetized cats, the solution of horseradish peroxidase was injected under the serosa of the indicated areas of colon. In 48 hours animals were transcardially perfused with a fixative solution. Sections of the medulla oblongata and the sacral spinal cord were stained using Mezulam's technique (1978). It was shown that all the areas of the colon studied received parasympathetic innervation from the neurons of the ventrolateral part of the vagus dorsal motor nucleus, which were uniform according to their morphometric characteristics. The number of neurons in this group, sending their axons to the ileocaecal area, was greater than the number of neurons, innervating ascending colon. Second group of neurons, that was represented by smaller cells, was located in the same part of the nucleus and innervated transverse colon. Transverse colon had an additional parasympathetic supply from the neurons of the spinal sacral parasympathetic nucleus.
the area of ileocaecal sphincter, ascending and transverse colon, were investigated. In urethane anaesthetized cats, the solution of horseradish peroxidase was injected under the serosa of the indicated areas of colon. In 48 hours animals were transcardially perfused with a fixative solution. Sections of the medulla oblongata and the sacral spinal cord were stained using Mezulam's technique (1978). It was shown that all the areas of the colon studied received parasympathetic innervation from the neurons of the ventrolateral part of the vagus dorsal motor nucleus, which were uniform according to their morphometric characteristics. The number of neurons in this group, sending their axons to the ileocaecal area, was greater than the number of neurons, innervating ascending colon. Second group of neurons, that was represented by smaller cells, was located in the same part of the nucleus and innervated transverse colon. Transverse colon had an additional parasympathetic supply from the neurons of the spinal sacral parasympathetic nucleus.
Keywords
About the authors
A A DOROFEYEVA
RAS L.P. Pavlov Institute of PhysiologyЛаборатория кортико-висцералыной физиологии; Институт физиологии им. И.П.Павлова РАН; RAS L.P. Pavlov Institute of Physiology
S S PANTELEYEV
RAS L.P. Pavlov Institute of PhysiologyЛаборатория кортико-висцералыной физиологии; Институт физиологии им. И.П.Павлова РАН; RAS L.P. Pavlov Institute of Physiology
F N MAKAROV
RAS L.P. Pavlov Institute of Physiologyлаборатория нейроморфологии; Институт физиологии им. И.П.Павлова РАН; RAS L.P. Pavlov Institute of Physiology
References
- Багаев В.А. и Макаров Ф.Н. Дорсальное моторное ядро блуждающего нерва и его роль в иннервации пищеварительного тракта. Морфология, 1997, т. 111,вып. 1, с. 7-14.
- Багаев В.А., Макаров Ф.Н., Рыбаков В.Л. и др. Локализация нейронов в дорсальном двигательном ядре блуждающего нерва, иннервирующих пилорическую область желудка. Докл. АН СССР, 1989, т. 304, № 4, с. 935-937.
- Багаев В.А., Макаров О.Н., Рыбаков В.Л. и др. Локализация нейронов, иннервирующих верхнюю часть двенадцатиперстной кишки, в дорсальном моторном ядре блуждающего нерва. Физиол. журн. СССР, 1991, т. 77, № 1, с. 45-52.
- Багаев В.А., Ноздрачев А.Д. и Пантелеев С.С. Ваговагальная рефлекторная дуга. Элементы структурно-функциональной организации. СПб., Изд-во Санкт-Петербургск. ун-та, 1997.
- Багаев В.А., Филиппова Л.В., Акоев Г.Н. и Макаров Ф.Н. Экстраорганные источники парасимпатической иннервации тонкой кишки в области связки Трейтца. Нейрофизиология, 1992, т. 24, №4, с. 423-430.
- Altschuler S.M., Escardo J., Lynn R.B. and Miselis R.R. The central organization of the vagus nerve innervating the colon of the rat. Gastroenterology, 1993, v. 104, p. 502-509.
- Altschuler S.M., Ferenci D.A., Lynn R.B. and Miselis R.R. Representation of the cecum in the lateral dorsal motor nucleus of the vagus nerve and commissural subnucleus of the nucleus tractus solitarii in rat. J. Сотр. Neurol., 1991, v. 304, №2, p. 261-274.
- Berthoud H.-R., Carlson N.R. and Powley T.L. Topography of efferent vagal innervation of the rat gastrointestinal tract. Am. J. Physiol., 1991, v. 260, p. 200-207.
- Berthoud H.-R., Jedrzejewska A. and Powley T.L. Simultaneous labeling of vagal innervation of the gut and afferent projections from the visceral forebrain with Dil injected into the dorsal vagal complex in the rat. J. Сотр. Neurol., 1990, v. 301, № 1, p. 65-79.
- Connors N.A., Sullivan J.M. and Kubb K.S. An autoradiographic study of the distribution of fibers from the dorsal motor nucleus of the vagus to the digestive tube of the rat. Acta Anat. (Basel)., 1933, v. 115,№3, p. 266-271.
- Hudson L.C. Horseradish peroxidase study of the location of extrinsic efferent and afferent neurons innervating the colon of dogs. Am. J. Vet. Res., 1990, v. 51, №11, p. 1875-1881.
- Mesulam M.-M. Tetramethylbenzidine for horseradish peroxidase neurohistochemistry: a non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents. J. Histochem.Cytochem., 1978, v. 26, №2, p. 106-117.
- Rostad H. Colonic motility in the cat. II. Extrinsic nervous control. Acta Physiol. Scand., 1973, v. 89, № 1, p. 91-103.
- Satomi H., Yamamoto Т., Ise H. and Takatama H. Origins of the parasympathetic preganglionic f.bers to the cat intestine as demonstrated by the horseradish peroxidase method. Brain Res., 1978, v.l51, №3, p. 571-578.
- Sugitani A.,Yoshida J., Nyhus LM.and Donahue P.E.Viscerotopic representation of preganglionic efferent vagus nerve in the brainstem of the rat: a Fluoro-Gold study. J. Auton. Nerv. Syst., 1991, v. 34, №2-3, p. 211-219.
Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).