NORMAL CONNECTIVE-TISSUE SKELETONOF THE PENIS AND ITS CHANGESIN PATIENTS WITH ERECTILE DYSFUNCTIONAND PEYRONIE'S DISEASE

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Abstract

The aim of this study was to examine the connective tissue of penis in normal individuals and in patients with erectile dysfunction
(ED) and Peyronie's disease (PD) using computer methods
of image analysis. Penis tissues were obtained from 20 males
aged 20-40 years who died in accidents, penis biopsies were
taken from 23 patients with ED and 9 patients with PD (average
age: 51±11,5 years). In both groups of patients, the volumetric
fraction of collagen fibers in the tunica albuginea and corpora
cavernosa was increased, while that one of elastic fibers was decreased.
At the same time, the changes of elastic fibers were noted: the fibers become thinner and formed rods. The reduction of the amplitude and the wavelength in the collagen fibers of the tunica
albuginea in patients with ED and the presence of fibrous plaques
in corpora cavernosa in in patients with PD were registered. The methods of computer image analysis may improve the morphologic
diagnosis of ED and PD.

About the authors

A I Neymark

V V Klimachev

V Ya Gerval'd

I P Bobrov

A M Avdalyan

H I Muzalevskaya

I V Gerval'd

P T Aliev

M A Kazymov

A I Neimark

Altai State Medical University

Altai State Medical University

V V Klimachev

Altai State Medical University

Altai State Medical University

V Ya Gervald

Altai State Medical University

Altai State Medical University

I P Bobrov

Altai State Medical University

Altai State Medical University

A M Avdalyan

Altai State Medical University

Altai State Medical University

N I Muzalevskaya

Altai State Medical University

Altai State Medical University

I V Gervald

Altai State Medical University

Altai State Medical University

R T Aliyev

Altai State Medical University

Altai State Medical University

M A Kazymov

Altai State Medical University

Altai State Medical University

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