PROLIFERATION MARKERSUSED IN HISTOLOGICAL STUDIES



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Abstract

The present paper reviews the current approaches used to study
cell proliferative activity. In the last years, a number of proteins
involved in cell cycle control were discovered, that may serve
as selective markers of proliferating cells. This work gives the characteristics of immunocytochemical methods demonstrating
5-bromodeoxyuridine, PCNA, Ki-67, FEN-1, phosphorylated
histone H3 and cyclins. The data on the role of these proteins in cell cycle control are presented.

About the authors

O V Kirik

Email: olga_kirik@mail.ru

G V Beznin

D E Korzhevskiy

O V Kirik

Institute of Experimental Medicine

Institute of Experimental Medicine

G V Beznin

Institute of Experimental Medicine

Institute of Experimental Medicine

D E Korzhevskiy

Institute of Experimental Medicine

Institute of Experimental Medicine

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