AGE-RELATED CHARACTERISTICS OF MELANOCYTES IN THE HAIR FOLLICLES OF THE TEMPORAL REGION SKIN IN MEN



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Abstract

Using morphometric and immunocytochemical methods, the distribution of melanin-containing cells in the hair follicles was studied using the autopsy samples of the skin obtained from the temporal region of scalp of 74 male individuals of different age only in the epithelial hair matrix - both in sections stained with hematoxylin-eosin and in sections treated with the monoclonal antibodies against tyrosinase. The examination of unstained sections demonstrated that after 15 years the reduction of a total area occupied by melanin granules in the cytoplasm of melanocytes and keratinocytes took place. After 26 years the irregular but stable decrease was found in the number of pigment-forming cells. The number of melanocytes identified using the monoclonal antibodies against tyrosinase, was greater then the number of pigment cell detected by routine methods.

References

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