H2S-POSITIVE NEURONS IN SOME NUCLEI OF CARDIOVASCULAR CENTER OF RAT BRAIN



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Abstract

The aims of this study were to investigate the presence of H2S-positive (H2S+) neurons and to study their distribution of in the nuclei of the medulla oblongata and the pons which are included in the cardiovascular center. Using immunocytochemical method to detect cystathionine β-synthase, the presence of H2S+ neurons was demonstrated in the nuclei studied of Wistar rats (n=16). More intense the reaction was detected in the large cells of motor nuclei, whereas the small cells of sensory nuclei usually had low-to-moderate enzyme activity. The data obtained provide a considerable amount of new information regarding the organization of brain nerve centers, including those controlling the cardiovascular system.

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