Email this article CAJAL BODY IN THE NEUROENDOCRINE NEURONS OF THE PALEOAMYGDALA
- Authors: Akhmadeyev A.V.1, Kalimullina L.B.1
-
Affiliations:
- Bashkir State University
- Issue: Vol 142, No 6 (2012)
- Pages: 063-065
- Section: Articles
- URL: https://j-morphology.com/1026-3543/article/view/399623
- DOI: https://doi.org/10.17816/morph.399623
- ID: 399623
Cite item
Open Access
Access granted
Abstract
The article demonstrates the ultrastructure of Cajal body (CB) that was detected during the electron microscopic study of nucleoplasm of the neuroendocrine neurons of the paleoamygdala of the adult Wistar rats in the study of the dynamics of their functional states throughout the estrous cycle. CB is located in the nucleoplasm close to the nucleolus and appears as a polygon structure, having the size of 0.4×0.5 μm, consisting of twisted strands of 40 to 60 nm thickness, which are separated from each other by the material of low electron density, obviously, a continuation of the nucleoplasm. Structural association of CB with other nuclear domains — nucleoli, interchro matin granule clusters were not noticed. CB was found in neurons only at the stage of «return to the initial state», which characterizes the completion of the functional activity of neurons. The number of these neurons was increased at the stage of metestrus. They are characterized by a segregation of nucleolar components, indicating the blockade of the protein synthesis. This fact is associated with the restructuring of CB modular organization, caused by the functional state of neurons.
Keywords
Full Text
About the authors
A. V. Akhmadeyev
Bashkir State University
Email: mpha@ufanet.ru
L. B. Kalimullina
Bashkir State University
References
- Ахмадеев А. В. и Калимуллина Л. Б. Электронно-микроскопическая характеристика нейроэндокринных нейронов миндалевидного тела мозга. Морфология, 2006, т. 130, вып. 6, с. 25–29.
- Патент РФ № 2438193. Способ приготовления переживающих срезов пириформной доли мозга. А. В. Ахмадеев иЛ. Б. Калимуллина. Заявка № 2007149137 от 25.12.2007 г. Опубл. в БИ, 2011, № 36, с. 215–220.
- Ченцов Ю. С. Введение в клеточную биологию. М., Академкнига, 2004.
- Bogolyubov D., Stepanova I. and Parfenov V. Universal nuclear domains of somatic and germ cells: some lessons from oocyte interchromatin granule cluster and Cajal body structure and molecular composition. BioEssays, 2009, v. 31, № 4, p. 400–409.
- Lafarga M., Andrés M. A., Fernández-Viadero C. et al. Number of nucleoli and coiled bodies and distribution of fibrillar centres in differentiating Purkinje neurons of chick and rat cerebellum. Anat. Embryol. (Berl.), 1995, v. 191, № 4, p. 359–367.
- Lemm I., Girard C., Kuhn A. N. and Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies. Mol. Biol. Cell., 2006, v. 17, № 7, p. 3221–3231.
- Mao Y. S., Zhang B. and Spector D. L. Biogenesis and function of nuclear bodies. Trends Genet., 2011, v. 27, № 8, p. 295–306.
- Matthews J., Wihlen B. and Tujague M. Estrogen receptor (ER) beta modulates ER alpha-mediated transcriptional activation by altering the recruitment of c-Fos and c-Jun to estrogen-responsive promoters. Mol. Endocrinol., 2006, v. 20, p. 533–543.
- Monneron A. and Bernhard W. Fine structural organization of the interphase nucleus in some mammalian cells J. Ultrastruct. Res., 1969, v. 27, № 3, p. 266–288.
- Nizami Z., Deryusheva S. and Gall J. G. The Cajal body and his tone locus body. Cold Spring Harb. Symp. Quant. Biol., 2010, v. 75, p. 313–320.
- Sleeman J. E., Lyon C. E., Platani M. et al. Dynamic interaction between splicing snRNPs, coiled bodies and nucleoli revealed using snRNP protein fusions to the green fluorescent protein. Exp. Cell Res., 1998, v. 243, № 2, p. 290–304.
Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).