Formation of plasma cell infiltrates in gingiva of patients with chronic apical periodontitis



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Abstract

The structure of leukocyte infiltrates in gingiva of 80 patients of various ages and gender with chronic apical periodontitis was studied using light microscopy with the application of monoclonal antibodies detecting CD38 antigen. Gingival tissues of practically of all the patients with periodontitis contained 2 types of leukocyte infiltrates: infiltrates with the low plasma cell content and high numbers of neutrophils and structures with high number of plasmocytes and low concentration of neutrophilic granulocytes. Within the gingival epithelium in patients with chronic apical periodontitis CD38 + cells were absent. The histogenesis of gingival leukocyte infiltrates in chronic apical periodontitis is discussed with the special emphasis on the role of plasma cells in the development of the pathological process.

About the authors

I V MAIBORODIN

Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

Email: imai@mail.ru, imai@ngs.ru
Центр новых медицинских технологий; Институт химической биологии и фундаментальной медицины СО РАН, г. Новосибирск; Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

A B VOITOVICH

Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

Email: imai@mail.ru, imai@ngs.ru
Центр новых медицинских технологий; Институт химической биологии и фундаментальной медицины СО РАН, г. Новосибирск; Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

Ye V KOZLOVA

Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

Email: imai@mail.ru, imai@ngs.ru
Центр новых медицинских технологий; Институт химической биологии и фундаментальной медицины СО РАН, г. Новосибирск; Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

I A KOLMAKOVA

Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

Email: imai@mail.ru, imai@ngs.ru
Центр новых медицинских технологий; Институт химической биологии и фундаментальной медицины СО РАН, г. Новосибирск; Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

I A PRITCHINA

Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

Email: imai@mail.ru, imai@ngs.ru
Центр новых медицинских технологий; Институт химической биологии и фундаментальной медицины СО РАН, г. Новосибирск; Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

D N KOVINTSEV

Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

Email: imai@mail.ru, imai@ngs.ru
Центр новых медицинских технологий; Институт химической биологии и фундаментальной медицины СО РАН, г. Новосибирск; Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

I S KOLESNIKOV

Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

Email: imai@mail.ru, imai@ngs.ru
Центр новых медицинских технологий; Институт химической биологии и фундаментальной медицины СО РАН, г. Новосибирск; Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

B V SHEPLEV

Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

Email: imai@mail.ru, imai@ngs.ru
Центр новых медицинских технологий; Институт химической биологии и фундаментальной медицины СО РАН, г. Новосибирск; Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

A N KOVINTSEV

Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

Email: imai@mail.ru, imai@ngs.ru
Центр новых медицинских технологий; Институт химической биологии и фундаментальной медицины СО РАН, г. Новосибирск; Institute of Chemical Biology and Fundamental Medicine, RAMS Siberian Branch, Novosibirsk

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