RAT MESOACCUMBOCINGULATE DOPAMINERGIC SYSTEM AND BRAIN EMOTIONAL FUNCTIONS



Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The authors suggest to distinguish the mesoaccumbocingulate dopaminergic system within the mesocorticolimbic dopaminergic system. It defines the formation of dependence on the influence of psychoactive drugs. The cortical center of the mesoaccumbocingulate dopaminergic system - anterior cingulate fields in rats (Сg1 and Cg3) - simultaneously represents the affective and motivation-mnestic center. The affective function of the rat anterior cingulate fields after the administration of psychoactive drugs, as well as the formation of dependence on them, is associated with the distribution of the dopaminergic endings of midbrain neurons in the nucleus accumbens and at the anterior cingulate fields, in particular, in the pregenual part.

About the authors

A V DROBLENKOV

Department of Human Anatomy, St. Petersburg State Pediatric Medical Academy

Department of Human Anatomy, St. Petersburg State Pediatric Medical Academy

N R KARELINA

Department of Human Anatomy, St. Petersburg State Pediatric Medical Academy

Department of Human Anatomy, St. Petersburg State Pediatric Medical Academy

V A LEBEDEV

Department of Human Anatomy, St. Petersburg State Pediatric Medical Academy

Department of Human Anatomy, St. Petersburg State Pediatric Medical Academy

References

  1. Вартанян Г.А. и Петров Е.С. Эмоции и поведение. Л., Наука, 1989.
  2. Голдберг Э. Управляющий мозг. М., Смысл, 2003.
  3. Блинков С.М. Лимбическая область. В кн.: Атлас цитоархитектоники коры большого мозга человека. М., Медгиз, 1955, с. 227-238.
  4. Дробленков А.В. Краткий микроскопический атлас ядерных и корковых центров мезокортиколимбической и некоторых других дофаминергических систем головного мозга крысы. СПб., изд. СПбГПМА, 2006.
  5. Дуус П. Топический диагноз в неврологии. Анатомия, физиология, клиника.. М., ИПЦ «Вазар Ферро», 1996.
  6. Романова Г.А., Шакова Ф.М., Ковалева О.И. и др. Сопоставление изменений поведения крыс и интегральных биохимических показателей, оцененных методом лазерной корреляционной спектрометрии, после фототромбоза префронтальной коры. Бюл. экспер. биол., 2004, т. 137, № 2, с. 156-159.
  7. Симонов П.В. Мотивированный мозг. М., Наука, 1987.
  8. Шабанов П.Д. Гормоны гипофизарной надпочечниковой сис темы в механизмах мозгового подкрепления и зависимости. В кн.: Основы нейроэндокринологии. СПб., Элби-СПб.; 2005, с. 147-203.
  9. Шабанов П.Д. и Калишевич С.Ю. Биология алкоголизма. СПб., Лань, 1998.
  10. Шабанов П.Д., Лебедев А.А. и Мещеров Ш. К. Дофамин и под крепляющие системы мозга. СПб., Лань, 2002.
  11. Шаляпина В.Г. Кортиколиберин и регуляция приспособительного поведения в патогенезе постстрессорной психопатологии. В кн.: Основы нейроэндокринологии. СПб., Элби-СПб, 2005, с. 84-146.
  12. Arnsten A.F., Cai J.X., Sterre J.S. and Golgman-Rakic P.S. Dopamine D2 receptor mechanisms contribute to age-related cognitive decline: the effects of quinpirole on memory and motor performance in monkeys. J. Neurosci., 1995, v. 15, p. 3429-3439.
  13. Beckstead R.M. An autoradiographic examination of corticocortical and subcortical projections mediodorsal (prefrontal) cortex of the rat. J. Comp. Neurol., 1979, v.184, p. 43-61.
  14. Bjorklund A. and Lindvall O. Dopamine-containing systems in the CNS. Handbook of neuroanatomy. Vol. 2: Classical neurotransmitters in the CNS, Part 1. Amsterdam - New York - Oxford: Elsevier Science Publishers, 1984, р. 55-122.
  15. Corbett D. Cocain enhances the reward value of medial prefrontal cortex stimulation. Neuroreport., 1991, v. 2, p. 805-808.
  16. Deacon T.W., Eitchendbaum H., Rosenberg P. and Eckmann K.W. Afferent connections of the prefrontal cortex in the rat. J. Comp. Neurol., 1983, v. 220, р. 168-190.
  17. Demeniere J.M., Piazza P.V., Guegan B.L. et al. Increased locomotor response to novelty and propensity to intravenous amphetamine self-administration in adult off-spring of stressed mothers. Brain Res., 1992, v. 586, p. 135-139.
  18. Devinsky O., Morrel M.J. and Vogt V.A. Contributions of anterior cingulated cortex to behaviour. Brain, 1995, v. 118, p. 279-306.
  19. Divac I. Patterns of subcortico-cortical projections as revealed by somatopetal horseradish peroxidase tracing. Neuroscience, 1979, v.4, p. 455-461.
  20. Donoghue J.P. and Henkerham M. Neostriatal projections from individual cortical fields conform to histochemically distinct striatal compartments in the rat. Brain Res., 1986, v. 365, p. 397-403.
  21. Goeders N. and Smith J. Cortical dopaminergic involvement in cocaine reinforcement. Science., 1983, v.221, p. 773-775.
  22. Hooks M.S., Colvin A.C., Juncos J.L. and Justice J.B. Individual differences in basal and cocaine stimulated extracellular dopamine in the nucleus accumbens using quantitative microdialysis. Brain Res., 1992, v. 587, p. 306-312.
  23. Ed.S.J. Richard et al. Human brain in function. 2-nd ed. Amsterdam etc.: Elsevier Acad. Press, 2004.
  24. Kolb B. Organization of the neocortex of the rat. In: Cerebral cortex of the rat. Cambridge: MIT Press, 1990, p. 21-33.
  25. Кolb B. and Walkey J. Behavioural and anatomical studies of the posterior parietal cortex in the rat. Behav. Brain Res., 1987, v.23, p. 127-145.
  26. Krettek J.E. and Price J.L. Projections from the amygdaloid complex to the cerebral cortex of the rat and cat. J. Comp. Neurol., 1977, v. 172, p. 687-722.
  27. Krettek J.E. and Price J.L. The cortical projections of the mediodorsal nucleus and adjacent thalamic nuclei in the rat. J. Comp. Neurol., 1977, v. 171, p.157-192.
  28. Kunishio K. and Haber S.N. Primate cingulostriatal projection: limbic striatal versus sensorimotor striatal input. J. Comp. Neurol., 1994., v. 350, p. 337-356.
  29. Nassif S., Cardo B., Lebersat B. and Velley L. Comparison of deficits in electrical self-stimulation after ibotenic acid lesion of the lateral hypothalamus and the medial prefrontal cortex. Brain Res., 1985, v. 341, № 2, p. 247-257.
  30. Рaper J.W. A proposed mechanism of emotion. Arch. Neurol. Psychiatry, 1937, v. 38, № 6, p. 725-743.
  31. Paxinos G. The rat brain in stereotaxic coordinates. Sydney, Orlando, San Diego, New-York, Austin, London, Montreal, Toronto, Academic press, 1986.
  32. Ramsey N.F. and Van Ree J.M. Reward and abuse of opiates. Pharmacol. Toxicol., 1992, v. 71, p. 81-84.
  33. Sawaguchi T., Goldman-Rakic P.S. The role of D1 receptor in working memory: local injections of dopamine antagonists into the prefrontal cortex of rhesus monkeys performing an oculomotor delayed-response task. J. Neurophysiol., 1994, v. 71, p. 515-528.
  34. Self D.W. and Stain L. Dopamine receptor subtypes in opioid and stimulant reward. Pharmacol. Toxicol., 1992, v. 49, p. 87-94.
  35. Swanson L.W. The hypothalamus. Handbook of chemical neuroanatomy. Amsterdam, New York, Oxford: Elsevier Science Publishers, 1987, v. 5, p. 1-104.
  36. Swanson L.W. A direct projection from Ammon horn to prefrontal cortex of the rat. Brain Res., 1981, v. 217, p. 150-154.
  37. Terreberry R.R. and Neafsey E.J. The rat medial; frontal cortex projects directly to autonomic regions of the brainstem. Brain Res. Bull., 1987, v. 19, p. 639-649.
  38. Van Hoesen G.W., Morecraft R.J. and Vogt B.A. Connections of the monkey cingulated cortex. In: Neurobiology of cingulated cortex and limbic thalamus: a comprehensive handbook. Boston, Birkhause, 1993, p. 249-284.
  39. Vogt B.A. and Miller M.W. Cortical connections between rat cingulated cortex and visual, motor and postsubicular cortices. J. Comp. Neurol., 1983, v. 216, p. 192-210.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 1970 Eco-Vector



СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: № 0110212 от 08.02.1993.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies