电邮这篇文章 CHANGES IN NEURONS AND GLIOCYTESOF RAT MESOACCUMBOCINGULATE SYSTEMFOLLOWING PERINATAL MORPHINEADMINISTRATION
- 作者: Droblenkov AV1, Karelina NR1, Shabanov PD1, Droblenkov AV2, Karelina NR3, Shabanov PD4
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隶属关系:
- St. Petersburg City Bureau of Forensic Medical Examination
- St. Petersburg State PediatricMedical Academy
- MedicalMilitary Academy
- 期: 卷 136, 编号 6 (2009)
- 页面: 35-37
- 栏目: Articles
- URL: https://j-morphology.com/1026-3543/article/view/399196
- DOI: https://doi.org/10.17816/morph.399196
- ID: 399196
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详细
morphometric parameters in mesoaccumbocingulate (MAC)
dopaminergic system of rats after pre- and postnatal opiate treatment, 0.1 mg dose of 1% morphine hydrochloride solution was injected into the fetal amnion of Wistar female rats (n=4) at Day 17 post fertilization and intraperitoneally into newborn rats (n=4)
at postnatal Day 4. Perinatal influence of morphine on MACsystem
in rats resulted in the chromophilic degeneration, swelling
and death of some part of neurons, decrease in the volume
of the other (slightly injured) neurons. Neuronal injury was more
pronounced after prenatal morphine treatment and was accompanied
by the increase in both microgliocyte cell number and phagocytic activity. Morphine administration induced no changes
in the satellite macrogliocyte number and in the average distance
between these cells and the bodies of slightly injured neurons.
作者简介
A Droblenkov
N Karelina
P Shabanov
A Droblenkov
St. Petersburg City Bureau of Forensic Medical ExaminationSt. Petersburg City Bureau of Forensic Medical Examination
N Karelina
St. Petersburg State PediatricMedical AcademySt. Petersburg State PediatricMedical Academy
P Shabanov
MedicalMilitary AcademyMedicalMilitary Academy
参考
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补充文件
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).