CHARACTERISTIC OF INNERVATION OF THE CHOROID PLEXUS OF HUMAN BRAIN LATERAL VENTRICLES



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Abstract

Objective - investigation of innervation of the choroid plexuses of human brain lateral ventricles. Material and methods. The research was performed on the autopsy material from 73 people (35 men aged from 27 to 94 years and 38 women aged from 44 to 96 years). Nerve fibers in the choroid plexus of the brain lateral ventricles were studied using immunohistochemical reactions demonstrating neuron-specific enolase (NSE), neurofilaments, myelin basic protein, neuropeptide Y, tyrosine hydroxylase and tumor marker S-100. Results. The branches of the anterior choroidal artery possess well-developed innervation before entering the tissue of the vascular plexuses. Neuromarkers NSE and S-100 were demonstrated in the epithelial cells of choroid plexus. S-100 protein was also detected in pericytes and dendritic cells. Conclusions. No nerve fibers and endings were found in the stroma of choroid plexus of the brain lateral ventricles. A hypothesis was formulated about the participation of pericytes and the role of epithelial and mast cell enzymes in the regulation of the functions of the choroid plexuses of the lateral ventricles.

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About the authors

O. A. Yuneman

Research Institute of Human Morphology

Email: ojunemann@yandex.ru
Laboratory of the Nervous System Development 3 Tsyurupi St., Moscow 117418

A. V. Pavlov

I. P. Pavlov Ryazan State Medical University

Department of Cardiovascular, Roentgenoendovascular, Operative Surgery and Topographic Anatomy 9 Vysokovol’tnaya St., Ryazan 390026

D. A. Otlyga

Research Institute of Human Morphology

Laboratory of the Nervous System Development 3 Tsyurupi St., Moscow 117418

S. V. Savelyev

Research Institute of Human Morphology

Laboratory of the Nervous System Development 3 Tsyurupi St., Moscow 117418

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