STRUCTURAL CHANGES IN THE SENSORY GANGLIA OF THE SPINAL NERVES AFTER REPEATED MAGNETIC STIMULATION ON THE MODEL OF ISCHEMIC MYELOPATHY



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Abstract

The aim of this study was to examine the association of morphological changes in the sensory ganglia of the spinal nerves (SGSN) with the cilinical symptomatology in rats with the experimentally induced ischemic myelopathy (IM), untreated or treated with repeated magnetic stimulation (RMS). The efficacy and mechanisms of RMS action on SGSN were studied by electron microscopy in 16 rats with IM. According to the results of treatment, in SGSN both at a distance from the damaged area (lumbar SGSN) and close to it (cervical SGSN) the morphological signs of regenerative-reparative processes were found in the cells and nerve fibers (restoration of the organelle structure in the cytoplasm o0f neurons and neurolemmocytes, the increase in the number of he latter and fiber remyelination). The expression of the structural changes correlated with the degree of functional recovery.

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About the authors

L. S. Onishchenko

S. M. Kirov Military Medical Academy

D. A. Iskra

S. M. Kirov Military Medical Academy

Email: iskradm@mail.ru

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