ASSESSMENT OF PERIPHERAL NERVE STATE BASED ON ACETYLCHOLINESTERASE ACTIVITY
- 作者: Karapetyan A.S.1, Rumyantseva T.A1, Lebedev P.V.1
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隶属关系:
- Yaroslavl’ State Medical Academy
- 期: 卷 146, 编号 6 (2014)
- 页面: 102-103
- 栏目: Articles
- URL: https://j-morphology.com/1026-3543/article/view/398859
- DOI: https://doi.org/10.17816/morph.398859
- ID: 398859
如何引用文章
详细
The aim of the study was to establish the possibility of assessment of the state of peripheral nerve based on acetylcholinesterase (AChE) activity. In a series of experiments on rats, the method for demonstration the of AChE activity on the sections of the peripheral nerves was modified (priority reference № 2013157128 of 23.12.13) and it was shown that the reaction intensity depended upon the state of the nerve fibers. During the atrophic processes, the enzyme activity decreased, while it was dramatically increased during fiber sprouting. It was shown that by using the intensity of AChE reaction as a criterion, the state of the nerve could be evaluated within 1-2 hours, which may be used later during the reconstructive operations (intraoperatively).
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作者简介
A. Karapetyan
Yaroslavl’ State Medical Academy
Email: а2311@inbox.ru
T. Rumyantseva
Yaroslavl’ State Medical Academy
Email: rum-yar@mail.ru
P. Lebedev
Yaroslavl’ State Medical Academy
Email: paw.lebedeff2011@yandex.ru
参考
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- Portincasa A., Gozzo G., Parisi D. et al. Microsurgical treatment of injury to peripheral nerves in upper and lower limbs: a critical review of the last 8 years. Microsurgery, 2007, v. 27, № 5, p. 455-462.
- Terzis J. K. An Exciting New Concept in Facial Reanimation. The Facial Nerve. Amsterdam, Kugler & Ghedini Publications, 1988.