NITROXIDERGIC CELLS OF THE RAT LUNG
- Authors: Syrtsova M.A.1
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Affiliations:
- Institute of Experimental Medicine
- Issue: Vol 150, No 6 (2016)
- Pages: 51-54
- Section: Articles
- URL: https://j-morphology.com/1026-3543/article/view/397801
- DOI: https://doi.org/10.17816/morph.397801
- ID: 397801
Cite item
Abstract
Using outbred male rats (n=20), the cells of the lung containing nitric oxide synthase (NOS) were identified. For this purpose, an immunocytochemical reaction demonstrating all three NOS isoforms was used. Tissue identification of NOS-containing cells was performed on the basis of study of their structure and localization. It was shown that nitric oxide synthesis in the lung can be carried out by the epithelial cells of the respiratory portion of the lung, the endothelium of the arteries and veins, alveolar macrophages, and special nitroxide-immunopositive structures not described previously, which resembled the neuroepithelial bodies by their organization. The tissue tissue attribution and the origin of the latter require further study. The data obtained confirm the possibility of demonstration of all cells containing different NOS isoforms by a single immunocytochemical reaction.
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References
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