THE SYSTEM OF NEUROENDOCRINE REGULATION OF AMYGDALA FUNCTIONS: THE ROLE OF DOPAMINE AND SEX STEROIDS



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Abstract

This review contains the data on the representation of dopaminergic system in the amygdala and its functional importance in the realization of neuroendocrine functions of the amygdala as a reproductive center. The evidence presented indicate the combined participation of dopamine and sex steroids in the regulation of amygdala activity, which exerts a modulating influence both on the centers of gonadotropin secretion and release and on centers of sexual behavior in the hypothalamic area of the brain. It is shown that a significant role in this process belongs to the chemosensory information coming to amygdala from the olfactory bulbs, in which the functional activity of dopaminergic system is also controlled by the amount of sex steroids. This review also presents the data indicating the changes in dopamine metabolism in amygdala structures in the process of formation of the stress-response, food, maternal, aggressive-defensive and deviant behavior.

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